Results 81 to 90 of about 99,376 (279)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Interpretation in Psychology and Social Science—New Approach or a Neglected Tradition?
The recent claims for an emergent interpretative paradigm in psychology and the social sciences is evaluated in the context of the long tradition of such methodologies in psychology.
Jochen Fahrenberg
doaj
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Analyzing Music Services Positioning Through Qualitative Research
Information technologies have produced new ways of distributing and consuming music, mainly by youth, in relation to both goods and services. In the case of goods, there has been a dramatic shift from traditional ways of buying and listening to music to ...
Manuel Cuadrado +2 more
doaj
PROJECTIVE PSYCHODIAGNOSTIC TECHNIQUES IN IDENTIFICATION OF MOTIVES FOR JUVENILE PROPERTY CRIMES
The article describes the meaning and peculiarities of the procedure of detection motive of property crime, committed by minors. It features the theoretical substantiation of the use of the projective method that lies in the basis of the identification ...
D. V. Ustinov, N. V. Ustinova
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Background. The article is dedicated to the use of projective techniques in the diagnosis of children with mental developmental delays. It highlights that initiating diagnostic assessments for these children is driven not only by challenges in mastering ...
Yulia T. Antonova +2 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The article focuses on the peculiarities of the professional self-determination of Ukrainian high school students in a risk society and a liquid modernity characterised by uncertainty, social instability and transformation in the field of education and ...
Bieliaieva V. O.
doaj +1 more source
Double node neighborhoods and families of simply connected 4-manifolds with b^+=1
We introduce a new technique that is used to show that the complex projective plane blown up at 6, 7, or 8 points has infinitely many distinct smooth structures. None of these smooth structures admit smoothly embedded spheres with self-intersection -1, i.
Fintushel, Ronald, Stern, Ronald J.
core

