Results 41 to 50 of about 75,331 (263)

BESZÁMOLÓ A „HÖLGYEK A TUDOMÁNYBAN 2020/2021 PROJEKT” EREDMÉNYEIRŐL

open access: yesKülönleges Bánásmód, 2022
A K+F Stúdió Kft. „Hölgyek a tudományban – 2020/2021” projektje a magyar Nemzeti Tehetség Program támogatásával valósul meg. Jelen tanulmány ennek a programnak az eredményeit mutatja be.
Katalin Mező
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Zarządzanie projektem partnerskim w kontekście powiązań klastrowych

open access: yesBarometr Regionalny, 2016
Powiązania klastrowe są środowiskiem stymulującym inicjowanie i realizację projektów partnerskich. Artykuł prezentuje wyniki badań przeprowadzonych w II kwartale 2015r wśród 13 aktywnych klastrów w woj.
Stanisław Krawiec, Magdalena Kutak
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

En problematisering af samspillet mellem centrale pædagogiske principper på arkitektuddannelsen

open access: yesDansk Universitetspaedagogisk Tidsskrift, 2013
Ud fra John Deweys erfaringspædagogik, bygget op om begreberne erfaring, situation og samspil, undersøges aspekter af en strukturel adskillelse af målstyrede og projektbaserede undervisningspraksisser med arkitektuddan­­nelsen på Kunstakademiets Skoler ...
Niels Grønbæk   +1 more
doaj   +2 more sources

Projekte

open access: yes, 2014
Ausgewählte aktuelle Forschungsvorhaben des IAB im ...
Dieter Wirth   +9 more
openaire   +2 more sources

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