Results 271 to 280 of about 10,824,096 (352)

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Dead or alive: how the immune system detects microbial viability

, 2019
Sander, L., Ugolini, M.
core   +1 more source

Microbial dynamics in coral reef waters: Diel cycles in contrasting seasons. [PDF]

Sci Adv
Steinsdóttir HGR, Akkaynak D, Frada MJ.
europepmc   +1 more source

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, EarlyView.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source

Cross-continental soil prokaryotic phenotypic traits driven by precipitation regime and land cover

Donhauser J, Han X, Doménech-Pascual A, Jordaan K, Casas-Ruiz J, Ramond J, Romaní A, Frossard A, Priemé A.   +8 more
europepmc   +1 more source

A molecular inventory of the faecal microbiomes of 23 marsupial species. [PDF]

Microb Genom
Bowerman KL, Soo RM, Chaumeil PA, Blyton MDJ, Sørensen M, Gunbilig D, Malig M, Islam M, Zaugg J, Wood DLA, Liachko I, Auch B, Morrison M, Krause L, Lindberg Møller B, Neilson EHJ, Hugenholtz P.   +16 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Comparison of picolyl azide-based BONCAT and microautoradiography for assessing the heterotrophic prokaryotic activity in the deep ocean

Amano C, Sintes E, Lebon N, Steiger J, Prijovic D, Reinthaler T, Obernosterer I, Bergauer K, Herndl GJ.   +8 more
europepmc   +1 more source

Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments. [PDF]

Genome Biol Evol
Sures K, Esser SP, Bornemann TLV, Moore CJ, Soares AR, Plewka J, Figueroa-Gonzalez PA, Ruff SE, Moraru C, Probst AJ.   +9 more
europepmc   +1 more source