Results 111 to 120 of about 98,174 (283)

Comparison of urinary prolactin and serum/urine prolactin ratio in hyperprolactinemic and macroprolactinemic patients

BMC Endocrine Disorders
Background Biologically, the monomeric form of prolactin is the most active. In measurement methods, all forms of prolactin are included in the assay; therefore, the presence of macroprolactin, causes a false increase in prolactin and misdiagnosis of ...
Behnam Ein-Mozaffari, Akbar Aliasgharzadeh, Farzad Najafipour, Azam Moslemi, Mitra Niafar, Vahideh Sadra, Nasser Aghamohammadzadeh, Jalil Houshyar, Halimeh Amirazad   +8 more
doaj   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Prolactin levels in antipsychotic treatment of patients with schizophrenia carrying the DRD2*A1 allele

, 2004
Background Hyperprolactinaemia induced by D2 dopamine receptor antagonist antipsychotic medication can result in significant health problems. \ud \ud Aims To examine the role of DRD2 polymorphism on prolactin levels in patients treated with antipsychotic
Burton, Simon C., Ritchie, Terry, Noble, Ernest P., Ward, Warren K., Barnes, Mark, Lawford, Bruce R., Young, Ross McD.   +6 more
core   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

Diagnostic Yield of Brain MRI in Pediatric Short Stature: Hypothalamic–Pituitary Lesions and Incidental Findings in Real‐World Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Background Brain MRI is widely performed in children with short stature or suspected growth hormone deficiency(GHD) to exclude hypothalamic–pituitary (HP) pathology, yet its diagnostic yield in routine practice is uncertain. We aimed to evaluate the prevalence, clinical significance, and distribution of HP and extrahypothalamic abnormalities ...
Mustafa Zubeidat, Tamer Sobeh, Shai Shrot   +2 more
wiley   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

A systematic review of breastfeeding prevalence, duration and determining factors in women with type 1 and type 2 diabetes mellitus

Diabetic Medicine, EarlyView.
Abstract Aims There is evolving evidence of the metabolic benefit of breastfeeding for women with diabetes and their infants but little data about breastfeeding prevalence and duration in women with type 1 and type 2 diabetes. This is the first systematic review to examine prevalence and duration of breastfeeding in women with pregestational diabetes ...
Fiona L. Britten, Emma Shipton, Madeline Duke, Emma L. Duncan, Leonie K. Callaway   +4 more
wiley   +1 more source

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber, Roemer B. Brandt, Mariël Leon Morales‐Grooters, Ronald van der Wal, Sjoerd A. A. van den Berg, Jelle J. Goeman, Antoinette Maassen van den Brink, Rolf Fronczek   +7 more
wiley   +1 more source

Biophysical Investigation of Prolactin

, 2013
This thesis investigates the biophysical properties of the pituitary hormone prolactin. The prolactin receptor is overexpressed in many types of cancer tissues, making prolactin a molecule of pharmacological interest.
Vang, Janus
core   +1 more source

Extrapituitary prolactin –1149 G/T promoter polymorphism in some rheumatoid arthritis patients

مجله كليه طب الكندي, 2015
Background: Prolactin is a hormone, as well as a cytokine which is synthesized and secreted from the anterior pituitary gland and various extra pituitary sites including immune cells under control of a superdistal promoter that contains a single ...
Adnan F. AL-Azzawie
doaj