Results 151 to 160 of about 84,239 (267)

Leptin and Acute Lung Disorders

open access: yesComprehensive Physiology, Volume 15, Issue 4, August 2025.
Leptin, an adipocyte‐derived cytokine‐like hormone, plays a crucial role in metabolism and immunity but its role in acute lung disorders such as acute respiratory distress syndrome (ARDS) remains controversial. Elucidating leptin's role in lung inflammation, and its interplay with metabolic disorders like obesity, will help designing therapeutical ...
Alice Huertas, Jahar Bhattacharya
wiley   +1 more source

Next Generation Sequencing Allows Identification of a Novel Mutation in the TfR2 Gene and Outperforms the Conventional Diagnostic Techniques

open access: yeseJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Introduction Type 3 hereditary hemochromatosis (HH) is a rare genetic disease due to mutations in the transferrin receptor 2 (TFR2) gene. Methods and Results Here, we describe the case of an Italian patient presenting with hyperferritinemia and hepatic iron accumulation, not evidenced by magnetic resonance imaging, that was subsequently ...
Miriam Longo   +9 more
wiley   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang   +7 more
wiley   +1 more source

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