Preeclampsia, a severe pregnancy‐induced disorder unique to humans, affects ∼5% of pregnancies globally. To understand the pathogenesis of preeclampsia, this study performed a comprehensive multi‐omics analysis of early pregnancy placental biopsies (chorionic villus samples) from pregnancies that later developed preterm/term preeclampsia, compared to ...
Ellen Menkhorst +13 more
wiley +1 more source
Protective effect of snail secretion filtrate in an in vitro model of mastitis
Abstract Background Bovine mastitis is inflammation of the mammary gland mainly caused by bacterial infections, with relevant economic costs and implications related to antibiotic resistance. In light of the increasing demand for sustainable therapies, this study evaluated the anti‐inflammatory and antioxidant effects of snail secretion filtrate (SSF ...
Gianluca Antonio Franco +5 more
wiley +1 more source
Effect of prolactin and growth hormone on prolactin and LH receptors in the dwarf mouse
Summary. Dwarf mice (DW/J; dw/dw) which exhibit a deficiency of prolactin and GH secretion were treated for 8 days with ovine prolactin and/or human GH (10 or 20 \g=m\g/day)and the effect on hepatic and testicular prolactin receptors was investigated. In
Friesen, H G +3 more
core
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo +10 more
wiley +1 more source
Tryptophan modulates the impact of prolactin on insomnia in perimenopausal women: a cross-sectional study. [PDF]
Yang S +16 more
europepmc +1 more source
Unexplained Elevated Vitamin B12: Consider Macro‐B12
ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans +3 more
wiley +1 more source
Hyperthyroidism, acromegaly, and hyperprolactinemia in a patient with a mature plurihormonal PIT-1 lineage adenoma. [PDF]
Ferreira de Carvalho J +5 more
europepmc +1 more source
Nonapeptide molecular evolution during the adaptive radiation of Tanganyika cichlids
Abstract Oxytocin (OT) and vasotocin (VT) are evolutionarily conserved nonapeptides that regulate a wide range of physiological and behavioral processes in vertebrates. Their receptor families have undergone gene duplications that facilitated functional diversification throughout vertebrate evolution.
Pol Sorigue +2 more
wiley +1 more source
Adjunctive aripiprazole for amisulpride-induced hyperprolactinemia: a preliminary retrospective study showing no reversing effect. [PDF]
Lan X, Zhuang H, Li P.
europepmc +1 more source

