Results 51 to 60 of about 98,174 (283)

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment

BMC Immunology, 2012
Background Prolactin is secreted from the pituitary gland and other organs, as well as by cells such as lymphocytes. Prolactin has an immunostimulatory effect and is associated with autoimmune diseases that are characterised by abnormal B cell activation,
Ledesma-Soto Yadira, Blanco-Favela Francisco, Fuentes-Pananá Ezequiel M, Tesoro-Cruz Emiliano, Hernández-González Rafael, Arriaga-Pizano Lourdes, Legorreta-Haquet María V, Montoya-Diaz Eduardo, Chávez-Sánchez Luis, Castro-Mussot María E, Chávez-Rueda Adriana K   +10 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Prolactin Hormone

Greenfort International Journal of Applied Medical Science
Prolactin (PRL) is mainly produced by pituitary lactotrophs and is tonically inhibited by the hypothalamus by the neurotransmitter dopamine. The discovery of multiple extra pituitary sites of PRL secretion also increases the range of known functions of ...
Rwida A. Emberesh, Qutaiba K. J. Alrawi
doaj   +1 more source

Night shift work and prolactin as a breast cancer risk factor

Medycyna Pracy, 2013
Prolactin - a hormone secreted in a circadian rhythm acts as a regulator of growth and development of the mammary glands. It has been observed that working at night increases breast cancer risk in women. Night shift work, probably carcinogenic to humans (
Agnieszka Bukowska, Beata Pepłońska
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]

, 2005
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J, Whitelaw C. B. A., ACCORSI, PIER ATTILIO, Hurley, W, Boutinaud, M, Kolb A., Allan G. A., Tonner, E, Wilde, C J, Boutinaud M., Wilde C. J., Beattie J., Accorsi, P A, Flint, D J, Flint D. J., Tonner E., Whitelaw, C B A, Hurley W., Kolb, A F, Allan, G J   +19 more
core   +1 more source

Prolactin-adjusted ACTH ratio in predicting lateralization of acth source during simultaneous bilateral inferior petrosal sinus sampling in patients with Cushing's disease

Indian Journal of Endocrinology and Metabolism, 2019
Introduction: Prolactin-adjusted adrenocorticotropic hormone (ACTH) ratio is used to improve the diagnostic accuracy of bilateral inferior petrosal sinus sampling (BIPSS) for lateralization of pituitary adenoma.
Kush Dev Singh Jarial, Anil Bhansali, Kanchan K Mukherjee, Rimesh Pal, Vivek Gupta, Akhilesh Sharma, Rakesh K Vasishta, Suja P Sukumar, Naresh Sachdeva, Rama Walia   +9 more
doaj   +1 more source

Resumption of Menses and Normalisation of Body Weight in Adolescents Undergoing Specialised Treatment for Anorexia Nervosa Inpatient or Outpatient Treatment

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To predict resumption of menses (ROM) in patients with anorexia nervosa (AN). Method Females aged 9–17 years with AN, receiving inpatient multimodal treatment (IMT) or family‐based treatment (FBT) underwent assessments at baseline, 6‐month and 12‐month follow‐up (12FU).
Annika Woltmann, Linus Imken, Vivien Kaiser, Johanna L. Keeler, Daniel Le Grange, Christoph U. Correll, Verena Haas   +6 more
wiley   +1 more source

Variation in prolactin is related to variation in sexual behavior and contact affiliation. [PDF]

PLoS ONE, 2015
Prolactin is associated with both maternal and paternal care and appears important in developing a bond between parent and infant. In contrast with oxytocin, another hormone important in infant care, there is scant information on the role of prolactin in
Charles T Snowdon, Toni E Ziegler
doaj   +1 more source