Results 81 to 90 of about 220,665 (364)
Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.
Genes & Development, 1997 Mice carrying a germ-line null mutation of the prolactin receptor gene have been produced by gene targeting in embryonic stem cells. Heterozygous females showed almost complete failure of lactation attributable to greatly reduced mammary gland ...
C. Ormandy +10 more
semanticscholar +1 more source
Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer [PDF]
, 2005 BACKGROUND: There is considerable interest in identifying target genes and chromatin binding sites for transcription factors in a genome-wide manner. Such information may become useful in diagnosis and treatment of disease, drug target identification ...
LeBaron, Matthew J +2 more
core +3 more sources
Molecular Nutrition &Food Research, EarlyView.(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez +5 more
wiley +1 more source
What can we learn from rodents about prolactin in humans?
Endocrine reviews, 2008 Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane receptor, a member of the cytokine receptor superfamily, and exerts its action via several interacting signaling pathways.
N. Ben-Jonathan +2 more
semanticscholar +1 more source
Emerging trends in the management of non‐obstructive azoospermia
UroPrecision, EarlyView.Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad +4 more
wiley +1 more source
Endocrine ConnectionsObjective: Serum prolactin measurements are important in the differential diagnosis of pituitary masses and subfertility. We observed discrepancies in serum prolactin levels in several patients measured with different immunoassays. Despite differences in
Yanaika S Sabogal Piñeros +4 more
doaj +1 more source
Surgical outcomes in male reconstructive urology: The Qatar experience
UroPrecision, EarlyView.Abstract Introduction Obstructive azoospermia (OA) is a prevalent cause of male infertility in Qatar and globally, with vasectomy reversal (VV) and vasoepididymostomy (VE) being the primary surgical treatments. While microsurgical techniques have advanced, data from the Middle East remain limited, influenced by the region's distinct demographic and ...
Kareim Khalafalla +8 more
wiley +1 more source
Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects.
Endocrine reviews, 1996 I. Introduction PRL affects more physiological processes than all other pituitary hormones combined. Among these are the regulation of mammary gland development, initiation and maintenance of lactation, immune modulation, osmoregulation, and behavioral ...
N. Ben-Jonathan +3 more
semanticscholar +1 more source
Canine pseudopregnancy: an evaluation of prevalence and current treatment protocols in the UK [PDF]
, 2018 Background: There is a dearth of literature on pseudopregnancy in the bitch, with only a few treatment-based studies published since the 1990s. Pseudopregnancy may be under-recognised in bitches and may account for a proportion of behavioural cases ...
A Bastan +38 more
core +1 more source
UroPrecision, EarlyView.Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit +2 more
wiley +1 more source