Results 101 to 110 of about 19,767 (298)

Excellent response to pasireotide therapy in an aggressive and dopamine-resistant prolactinoma.

European Journal of Endocrinology, 2019
Prolactinomas are the most commonly encountered pituitary adenomas in the clinical setting. While most can be controlled by dopamine agonists, a subset of prolactinomas are dopamine-resistant and very aggressive.
Eva C. Coopmans, Sebastiaan W F van Meyel, K. Pieterman, J. V. Ipenburg, L. Hofland, E. Donga, A. Daly, A. Beckers, A. J. V. D. Lely, S. Neggers   +9 more
semanticscholar   +1 more source

ACT001 Inhibits Tumor Progression and Modulates Immune Responses in Non‐Small Cell Lung Cancer

Journal of Clinical Laboratory Analysis, Volume 39, Issue 17, September 2025.
ACT001, a novel small‐molecule inhibitor, demonstrates significant antitumoral and immunomodulatory effects in NSCLC by inhibiting cell proliferation, migration, and invasion, inducing cell cycle arrest, and suppressing tumor growth. Mechanistically, it targets STAT1/STAT3, reduces PD‐L1 expression, and enhances granzyme B release in CD3+ T cells ...
Zhijing Shi, Yiman Li, Huijie Hou, Zhitao Wang, Hui Guo, Yang Yu, Yan Song, Zhe Chen   +7 more
wiley   +1 more source

Etiology, functional status and short term outcome of patients with pituitary lesions. An experience from a developing country [PDF]

, 2009
OBJECTIVE: To describe the etiology, functional status and short term outcome of patients with pituitary lesions (PL). METHODS: Brain or pituitary MRI reports of 3753 patients were analyzed for PL over the period of 2000 to 2007, done at the Aga Khan ...
Haq, Mansoor Ul, Ishtiaq, Osama, Jabbar, Abdul, Masood, Mohammad Qamar, Mehar, Saeed, Rizwan, Azra   +5 more
core   +1 more source

Male, Female, Other: Transgender and the Impact in Primary Care [PDF]

, 2016
Transgender includes patients at various stages of their journey. It is important that providers care for transgender patients with a culturally sensitive approach, awareness, and competent skill. There are new terms to learn.
Markwick, Laura
core   +2 more sources

Mitochondria as Regulators of Nonapoptotic Cell Death in Cancer

MedComm, Volume 6, Issue 8, August 2025.
Mitochondrial fission and fusion are key processes in maintaining cellular health. Fission is driven by proteins like, Fis‐1, which recruits DRP‐1, to facilitate the division of mitochondria. Fusion, however, is mediated by mitofusion 1(MFN1), mitofusion 2(MFN2), and optic atrophy 1 (OPA1), which work together to merge mitochondria, allowing functional
Saloni Malla, Rabin Neupane, Saloni Sood, Noor Hussein, Mariam Abou‐Dahech, David Terrero, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +8 more
wiley   +1 more source

Patient Participation in Urine Specific Gravity Screening for Arginine Vasopressin Deficiency in an Inpatient Neurosurgical Clinic

Clinical Endocrinology, Volume 103, Issue 2, Page 201-208, August 2025.
ABSTRACT Objective Detecting hypotonic urine (specific gravity < 1005 g/L) is crucial for the early identification of arginine vasopressin deficiency (AVP‐deficiency), a common complication after pituitary surgery. This study aimed to evaluate the agreement between urine specific gravity measurements taken by patients using urine test strips and those ...
Jeanne‐Marie Nollen, Anja H. Brunsveld‐Reinders, Nienke R. Biermasz, Marco J. T. Verstegen, Eline Leijtens, Wilco C. Peul, Ewout W. Steyerberg, Wouter R. van Furth   +7 more
wiley   +1 more source

Multifunctional Bone Morphogenetic Protein System in Endocrinology [PDF]

, 2013
New biological activities of bone morphogenetic proteins (BMPs) in the endocrine system have recently been revealed. The BMP system is composed of approximately 30 ligands and preferential combinations of type I and type II receptors.
Otsuka, Fumio
core   +1 more source

Discordance Between Prolactinoma Size and Prolactin Level: An Unusual Laboratory Finding [PDF]

, 2021
Wafa Dawaher, Sabah Patel, Zubina Unjom, Alvia Moid, Janice L Gilden, Victoria Trendafilova   +5 more
openalex   +1 more source

MiR‐20a‐5p Inhibits Bladder Cancer Proliferation and Migration by Targeting KPNA2

Journal of Cellular and Molecular Medicine, Volume 29, Issue 16, August 2025.
ABSTRACT Bladder cancer (BC) is one of the 10 most common cancers in the world, and its recurrence and metastasis are the main causes of death in BC patients. Exploring the molecular mechanisms of BC pathogenesis and searching for new prognostic markers and therapeutic targets are important for improving patient prognosis.
Shuai Ye, Cen Liufu, Cong Yin, Tao Zhu, Jinqing He, Yuanyuan Tian, Yan Wang, Bentao Shi   +7 more
wiley   +1 more source

Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole

Endocrinology, Diabetes & Metabolism Case Reports, 2016
In this report, we describe a female patient with both prolactinoma and psychotic disorder who was successfully treated with aripiprazole, a partial dopamine 2 receptor agonist.
Ilse C A Bakker, Chris D Schubart, Pierre M J Zelissen   +2 more
doaj   +1 more source