Results 101 to 110 of about 17,963 (297)

EGFR and JAK2 were significant master gene biomarkers in invasive and noninvasive pituitary adenoma

Precision Medical Sciences, Volume 14, Issue 1, Page 4-14, March 2025.
(A) Visualization of the interactions between upregulated and downregulated genes in invasive and non‐invasive pituitary adenomas, highlighting the central role of EGFR and JAK2 as master gene biomarkers. (B) Expression density plots show the distribution of gene expression values after normalization, and volcano plots illustrate significant DEGs ...
Afsaneh Ghasemi, Zhila Fereidouni, Fahimeh Maleki‐Sheikhabadi, Fateme Shariati Far, Roya Dokoohaki, Hamid Zaferani Arani, Ahmad Bereimipour   +6 more
wiley   +1 more source

Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole

Endocrinology, Diabetes & Metabolism Case Reports, 2016
In this report, we describe a female patient with both prolactinoma and psychotic disorder who was successfully treated with aripiprazole, a partial dopamine 2 receptor agonist.
Ilse C A Bakker, Chris D Schubart, Pierre M J Zelissen   +2 more
doaj   +1 more source

Peptide receptor radionuclide therapy with somatostatin analogs beyond gastroenteropancreatic neuroendocrine tumors

Journal of Neuroendocrinology, Volume 37, Issue 3, March 2025.
The thera(g)nostic approach with somatostatin analog‐based agents extends beyond gastroenteropancreatic neuroendocrine tumors. Understanding tumor biological mechanisms is essential for optimizing treatment strategies. Abstract First isolated by Brazeau et al. in 1972, somatostatin (SST) is a neuropeptide known for regulating various signaling pathways
Giulia Santo, Gianpaolo di Santo, Francesco Cicone, Irene Virgolini   +3 more
wiley   +1 more source

Giant Prolactinomas [PDF]

Neuroendocrinology, 2018
Prolactin-secreting adenomas (prolactinomas) are the most common secreting adenomas of the pituitary. Microprolactinomas (diameter <10 mm) are frequently diagnosed in women, whereas macroprolactinomas (maximum diameter ≥10 mm) are generally seen in men. Most macroprolactinomas measure between 10 and 40 mm.
openaire   +2 more sources

Pituitary apoplexy: re-evaluation of risk factors for bleeding into pituitary adenomas and impact on outcome [PDF]

, 2011
Objective: To assess frequency, symptoms and outcome of pituitary apoplexy (PA) among pituitary adenoma patients, to gain better insight into risk factors for bleeding into pituitary adenoma, and to estimate the sequelae of PA by means of a matched ...
Ayuk, Bao, Bills, Biousse, Bjerre, Bonicki, Cardoso, Christoph Schmid, da Motta, Diane L Möller-Goede, Dubuisson, Jeffcoate, Klara Landau, Liu, Lohrer, McCabe, McNEMAR, Michael Brändle, Nielsen, Nomikos, Onesti, Randeva, Rene L Bernays, Semple, Wakai, Zayour   +25 more
core   +1 more source

mRNA–miRNA integration analysis of T‐cell exhaustion in sepsis from community‐acquired pneumonia

Acute Medicine &Surgery, Volume 12, Issue 1, January/December 2025.
mRNA–miRNA integration analysis in community‐acquired pneumonia‐associated sepsis revealed immune dysregulation with T‐cell exhaustion, highlighting the activation of PD‐1/PD‐L1 and suppression of Th1 pathways. These findings provide insights into sepsis pathogenesis and potential therapeutic targets.
Sayaka Oda, Hisatake Matsumoto, Yuki Togami, Jumpei Yoshimura, Hiroshi Ito, Shinya Onishi, Arisa Muratsu, Yumi Mitsuyama, Daisuke Okuzaki, Hiroshi Ogura, Susumu Tanaka, Jun Oda   +11 more
wiley   +1 more source

THE EFFECT OF RALOXIFENE ON SERUM PROLACTIN LEVEL IN PATIENTS WITH PROLACTINOMA.

Endocrine Practice, 2019
Objectives To evaluate the effect of raloxifene on prolactin levels in addition to dopamine agonist (DA) therapy in patients with prolactinoma. Methods We conducted a retrospective chart review of 14 patients with prolactinoma on stable dose of DA for 6 ...
Chitra Choudhary, A. Hamrahian, J. Bena, P. Recinos, L. Kennedy, Georgiana Dobri   +5 more
semanticscholar   +1 more source

Drug‐Induced Hyperprolactinemia and Granulomatous Mastitis: A Case Report and Literature Review

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Granulomatous mastitis (GM) is a rare inflammatory condition of the breast that can mimic inflammatory breast cancer. We report a case of a 54‐year‐old female who developed recurrent GM symptoms in the context of drug‐induced hyperprolactinemia, which resolved with dopamine agonist therapy.
Mohammed Alenazi, Sarah Howse, Syed Ali Imran, Priya Gusain   +3 more
wiley   +1 more source

Epidemiologia dos cancros colorectal e do estômago no sul de Portugal:um contributo da modelação estatística em dados oncológicos [PDF]

, 2016
O peso que as neoplasias do estômago, cólon e reto assumem na sociedade portuguesa, em particular na região sul de Portugal, foi um dos elementos que motivou o presente estudo que tem por objetivo analisar tendências, projeções, sobrevivências relativas ...
São João, Ricardo
core  

Pituitary adenomas, some diagnostic and therapeutical aspects [PDF]

, 1994
The treatment of almost all types of pituitary adenomas has changed considerably in recent years. New types of drugs as well as improved application forms of older drug therapies are now becoming more and more available for everyday treatment of patients
Herder, W.W. (Wouter) de, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der   +2 more
core   +1 more source