Impact of Nano-Bromocriptine on Egg Production Performance and Prolactin Expression in Layers [PDF]
Animals, 2021 The current study aimed to investigate the potential use of nano-bromocriptine in improving the laying performance of late laying hens by modulating the prolactin gene expression.
Ahmed Dawod +7 more
doaj +2 more sources
The impact of vaginal bromocriptine on reducing pain and menstrual bleeding in women with adenomyosis: a randomized controlled trial [PDF]
Scientific ReportsBromocriptine, a dopamine receptor agonist that suppresses prolactin secretion from the pituitary gland, is an inexpensive and widely accessible medication with few adverse effects.
Parvin Hakimi +3 more
doaj +2 more sources
Impact of bromocriptine withdrawal timing on pregnancy outcomes in patients with pituitary prolactin-secreting microadenomas: a real-world retrospective study of 188 pregnancies in China [PDF]
Frontiers in PharmacologyBackgroundThis study aims to evaluate the influence of the timing for bromocriptine withdrawal in pregnant women with pituitary prolactin-secreting microadenomas.MethodsIn this retrospective study,188 pregnant women diagnosed with pituitary prolactin ...
Jiao Lan +14 more
doaj +2 more sources
Pharmacokinetics of oral bromocriptine in postpartum patients [PDF]
PregnancyIntroduction Cardiomyopathy is a leading cause of maternal morbidity and mortality. A prolactin fragment has been implicated in the pathogenesis, and preliminary data suggest that bromocriptine—a dopamine receptor agonist that inhibits prolactin ...
Rachel Sinkey +7 more
doaj +2 more sources
Bromocriptine in peripartum cardiomyopathy: A meta‐analysis with trial sequential analysis [PDF]
ESC Heart FailureBromocriptine has been proposed as a disease‐modifying therapy for peripartum cardiomyopathy (PPCM). The long‐term outcomes of bromocriptine use remain uncertain.
Umar G. Adamu +3 more
doaj +2 more sources
Clinical response and patient's tolerance of vaginal versus oral bromocriptine in women who suffers hyperprolactinaemia [PDF]
Zagazig University Medical Journal, 2021 Hyperprolactinaemia is areal challenge for gynecologist and endocrinologists ,bromocriptine was used for treating hyperprolactinaemia ,bromocriptine associated with many side effect this study aimed to compare clinical response , side effects and ...
mostafa abdelfattah +3 more
doaj +1 more source
Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
iScience, 2022 Summary: Bromocriptine is approved as a diabetes therapy, yet its therapeutic mechanisms remain unclear. Though bromocriptine’s actions have been mainly attributed to the stimulation of brain dopamine D2 receptors (D2R), bromocriptine also targets the ...
Despoina Aslanoglou +14 more
doaj +1 more source
Study on Synergistic Effect of Bromocriptine and Sitagliptin in Streptozotocin-induced Diabetic Rats [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. Restoration of euglycemia in type 2 diabetes mellitus is difficult to achieve due to its multifactorial pathogenesis and frequently requires multiple ...
Govindaraj Nileshraj +3 more
doaj +1 more source
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas
BMC Endocrine Disorders, 2021 Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creating ...
Shuman Wang +6 more
doaj +1 more source
Bromocriptine monotherapy overcomes prostate cancer chemoresistance in preclinical models
Translational Oncology, 2023 Chemoresistance is a major obstacle in the clinical management of metastatic, castration-resistant prostate cancer (PCa). It is imperative to develop novel strategies to overcome chemoresistance and improve clinical outcomes in patients who have failed ...
Lijuan Bai +15 more
doaj +1 more source