Results 1 to 10 of about 11,189 (206)

<i>Artemisia argyi</i> Extracts Modulate Prolactin and Prostaglandin Pathways in Estrogen-Stimulated GH3 Cells and a Hyperprolactinemia Mouse Model. [PDF]

Food Sci Nutr
Artemisia argyi extracts suppress prolactin secretion, restore reproductive hormones, and modulate prostaglandin balance and inflammation in GH3 cells and a hyperprolactinemia mouse model. ABSTRACT Artemisia argyi (Pyeong‐an‐ae) has long been used in traditional medicine for gynecological conditions; however, its efficacy in treating premenstrual ...
Ma MJ, Lee J, Park J, Son D, Kim HJ, Jo YH, Lee SB, Kim GD, Choi EJ, Seo MS, Choi JH.   +10 more
europepmc   +2 more sources

Impact of bromocriptine withdrawal timing on pregnancy outcomes in patients with pituitary prolactin-secreting microadenomas: a real-world retrospective study of 188 pregnancies in China [PDF]

Frontiers in Pharmacology
BackgroundThis study aims to evaluate the influence of the timing for bromocriptine withdrawal in pregnant women with pituitary prolactin-secreting microadenomas.MethodsIn this retrospective study,188 pregnant women diagnosed with pituitary prolactin ...
Jiao Lan, Jiao Lan, Peng Hong, Peng Hong, Wei Huang, Wei Huang, Aiyun Xing, Aiyun Xing, Peizhi Zhou, Jing Tan, Jing Tan, Xue Peng, Xue Peng, Jing Fu, Jing Fu   +14 more
doaj   +2 more sources

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma. [PDF]

Clin Transl Med
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Xie F, Gu L, Yang K, Wang S, Xiao M, Yan G, Zhang Q, Liang R, Zhuang A, Xi Z, Niu Y, Chen Y, Xia X, Qu L, Zhao B, Li W, Wu T, Yu C, Luo C, Wang H, Lian L, Li W.   +21 more
europepmc   +2 more sources

Bromocriptine in peripartum cardiomyopathy: A meta‐analysis with trial sequential analysis [PDF]

ESC Heart Failure
Bromocriptine has been proposed as a disease‐modifying therapy for peripartum cardiomyopathy (PPCM). The long‐term outcomes of bromocriptine use remain uncertain.
Umar G. Adamu, Kabo Mojela, Kamilu M. Karaye, Nqoba Tsabedze   +3 more
doaj   +2 more sources

Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors [PDF]

Journal of Nanobiotechnology
Intranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang, Guangyu Jia, Qi Wang, Yamei Yu, Xiaolong Tang, Heqing Zheng, Xinyu Yang, Yao Xiao, Yangrui Ou, Jingjing Jiang, Hua Guo, Ye Wang, Shiyong Li   +12 more
doaj   +2 more sources

Management of posttraumatic refractory paroxysmal sympathetic hyperactivity with bromocriptine: a case report [PDF]

Journal of Trauma and Injury
This case report describes a unique instance of refractory paroxysmal sympathetic hyperactivity (PSH) in a 19-year-old woman following a traumatic brain injury sustained in a motorcycle accident.
Min-Seok Woo, Seong-Hyun Park, Jeong-Hyun Hwang, Chaejin Lee   +3 more
doaj   +2 more sources

Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine

iScience, 2022
Summary: Bromocriptine is approved as a diabetes therapy, yet its therapeutic mechanisms remain unclear. Though bromocriptine’s actions have been mainly attributed to the stimulation of brain dopamine D2 receptors (D2R), bromocriptine also targets the ...
Despoina Aslanoglou, Suzanne Bertera, Laura Friggeri, Marta Sánchez-Soto, Jeongkyung Lee, Xiangning Xue, Ryan W. Logan, J. Robert Lane, Vijay K. Yechoor, Peter J. McCormick, Jens Meiler, R. Benjamin Free, David R. Sibley, Rita Bottino, Zachary Freyberg   +14 more
doaj   +1 more source

Study on Synergistic Effect of Bromocriptine and Sitagliptin in Streptozotocin-induced Diabetic Rats [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. Restoration of euglycemia in type 2 diabetes mellitus is difficult to achieve due to its multifactorial pathogenesis and frequently requires multiple ...
Govindaraj Nileshraj, Chandrasekaran Swithraa, Murugesan Sakthibalan, Maruti Shripati Sawadkar   +3 more
doaj   +1 more source

The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas

BMC Endocrine Disorders, 2021
Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creating ...
Shuman Wang, Aihua Wang, Yu Zhang, Kejing Zhu, Xiong Wang, Yonggang Chen, Jinhu Wu   +6 more
doaj   +1 more source

Impact of Nano-Bromocriptine on Egg Production Performance and Prolactin Expression in Layers

Animals, 2021
The current study aimed to investigate the potential use of nano-bromocriptine in improving the laying performance of late laying hens by modulating the prolactin gene expression.
Ahmed Dawod, Noha Osman, Hanim S. Heikal, Korany A. Ali, Omaima M. Kandil, Awad A. Shehata, Hafez M. Hafez, Hamada Mahboub   +7 more
doaj   +1 more source