Results 261 to 270 of about 17,963 (297)
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Neurosurgery, 1991
Abstract Six cases of malignant prolactinoma have been reported; an additional two cases are presented here and the literature is reviewed. Diagnosis rests upon evidence of metastasis rather than histological criteria perse. Cases have arisen from known adenomas, particularly the invasive type. Bromocriptine is a useful palliative.
E A, Popovic +5 more
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Abstract Six cases of malignant prolactinoma have been reported; an additional two cases are presented here and the literature is reviewed. Diagnosis rests upon evidence of metastasis rather than histological criteria perse. Cases have arisen from known adenomas, particularly the invasive type. Bromocriptine is a useful palliative.
E A, Popovic +5 more
openaire +2 more sources
Annual Review of Medicine, 1989
Prolactinomas are the most common of the hormone-secreting pituitary tumors and must be distinguished from nonsecreting tumors causing hyperprolactinemia by hypothalamic or stalk dysfunction. For both micro- and macroadenomas, dopamine agonists appear to be the treatment of choice, transsphenoidal surgery being reserved for nonresponders.
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Prolactinomas are the most common of the hormone-secreting pituitary tumors and must be distinguished from nonsecreting tumors causing hyperprolactinemia by hypothalamic or stalk dysfunction. For both micro- and macroadenomas, dopamine agonists appear to be the treatment of choice, transsphenoidal surgery being reserved for nonresponders.
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Best Practice & Research Clinical Endocrinology & Metabolism, 2009
This review focus on the epidemiology, diagnosis and treatment of prolactinomas. In particular, attention was given to recent data showing a high prevalence of these tumours in the general population, 3-5 times higher than previously reported. The diagnosis of hyperprolactinaemia has been simplified in recent years, and only prolactin (PRL) assay and ...
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This review focus on the epidemiology, diagnosis and treatment of prolactinomas. In particular, attention was given to recent data showing a high prevalence of these tumours in the general population, 3-5 times higher than previously reported. The diagnosis of hyperprolactinaemia has been simplified in recent years, and only prolactin (PRL) assay and ...
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Clinical Endocrinology, 2020
To report the clinical presentation, management and outcomes of young patients with prolactinomas (
V. Arya +10 more
semanticscholar +1 more source
To report the clinical presentation, management and outcomes of young patients with prolactinomas (
V. Arya +10 more
semanticscholar +1 more source
Clinical Endocrinology, 1991
The management of prolactinomas requires a complex interaction of medical, surgical and radiotherapeutic intervention. With the judicious use of all these modalities, patients can usually be managed with great success and, perhaps more importantly, their presenting complaints (gonadal dysfunction and infertility) are usually completely corrected.
David Cunnah, Michael Besser
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The management of prolactinomas requires a complex interaction of medical, surgical and radiotherapeutic intervention. With the judicious use of all these modalities, patients can usually be managed with great success and, perhaps more importantly, their presenting complaints (gonadal dysfunction and infertility) are usually completely corrected.
David Cunnah, Michael Besser
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MANAGEMENT AND OUTCOMES OF GIANT PROLACTINOMA: A SERIES OF 71 PATIENTS.
Endocrine Practice, 2019Objective: To describe outcomes of patients with giant prolactinoma (≥4 cm) and identify predictors of therapeutic response. Methods: In this retrospective study, complete biochemical and structural response were defined as prolactin (PRL) ≤25 ng/mL and ...
Oksana Hamidi +11 more
semanticscholar +1 more source
2017
Prolactinomas account for approximately 50% of all pituitary adenomas coming to medical attention and are an important cause of hypogonadism and infertility. They may also be responsible for mass effects. Nevertheless, prolactinomas are not the only case of hyperprolactinemia: many physiological and pathological conditions (pregnancy, medications ...
Philippe Chanson, Dominique Maiter
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Prolactinomas account for approximately 50% of all pituitary adenomas coming to medical attention and are an important cause of hypogonadism and infertility. They may also be responsible for mass effects. Nevertheless, prolactinomas are not the only case of hyperprolactinemia: many physiological and pathological conditions (pregnancy, medications ...
Philippe Chanson, Dominique Maiter
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Clinical Endocrinology, 1995
SummaryBACKGROUND Apart from the rare association with type I multiple endocrine neoplasia (MEN‐1), familial types of prolactinoma have not been reported.PATIENTS AND MEASUREMENTS Eight hyperprolacti‐naemic patients in four families and 18 of their first and second‐degree relatives (parents, children and grandchildren) were examined.
M, Berezin, A, Karasik
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SummaryBACKGROUND Apart from the rare association with type I multiple endocrine neoplasia (MEN‐1), familial types of prolactinoma have not been reported.PATIENTS AND MEASUREMENTS Eight hyperprolacti‐naemic patients in four families and 18 of their first and second‐degree relatives (parents, children and grandchildren) were examined.
M, Berezin, A, Karasik
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Acta Endocrinologica, 1992
Malignant prolactinoma is a rare entity and only a few cases have been published. The diagnostic criteria and the clinical course remain unclear. We present a case of malignant prolactinoma in a woman with a 30-year duration of the disease. In the terminal stage of the disease the prolactinoma metastasized to the left eye, the prolactin level reaching ...
M, Berezin +4 more
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Malignant prolactinoma is a rare entity and only a few cases have been published. The diagnostic criteria and the clinical course remain unclear. We present a case of malignant prolactinoma in a woman with a 30-year duration of the disease. In the terminal stage of the disease the prolactinoma metastasized to the left eye, the prolactin level reaching ...
M, Berezin +4 more
openaire +2 more sources
CircOMA1 modulates cabergoline resistance by downregulating ferroptosis in prolactinoma
Journal of Endocrinological Investigation, 2023N. Wu +8 more
semanticscholar +1 more source