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The Netherlands journal of medicine, 2010
Prolactinomas are a frequent cause of gonadal dysfunction and infertility, especially in women. Dopamine agonists are first-line therapy and their efficacy in the treatment of prolactinomas is well established. Current challenges related to the management of prolactinomas remain in the recurrence of the disease after withdrawal of dopamine agonists ...
Kars, M. +3 more
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Prolactinomas are a frequent cause of gonadal dysfunction and infertility, especially in women. Dopamine agonists are first-line therapy and their efficacy in the treatment of prolactinomas is well established. Current challenges related to the management of prolactinomas remain in the recurrence of the disease after withdrawal of dopamine agonists ...
Kars, M. +3 more
openaire +3 more sources
New England Journal of Medicine, 1979
The secretion of prolactin is tonically inhibited by the hypothalamus, an effect mediated by the release of a prolactin inhibitory factor into the pituitary blood supply.1 Much newly acquired evidence points to dopamine as the principal inhibitory regulator.2 Specific dopamine-containing nerve tracts in the hypothalamus terminate on the blood vessels ...
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The secretion of prolactin is tonically inhibited by the hypothalamus, an effect mediated by the release of a prolactin inhibitory factor into the pituitary blood supply.1 Much newly acquired evidence points to dopamine as the principal inhibitory regulator.2 Specific dopamine-containing nerve tracts in the hypothalamus terminate on the blood vessels ...
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Annales d'Endocrinologie, 2007
Surgery is generally used as second-line treatment in prolactinomas. For microprolactinomas, it may be indicated in cases of resistance or intolerance to dopamine agonists or where patients prefer definitive cure to lifelong drug treatment. In highly trained hands, selective adenomectomy results in normalization of prolactin levels in 75-90% of cases ...
M, Jan, H, Dufour, T, Brue, P, Jaquet
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Surgery is generally used as second-line treatment in prolactinomas. For microprolactinomas, it may be indicated in cases of resistance or intolerance to dopamine agonists or where patients prefer definitive cure to lifelong drug treatment. In highly trained hands, selective adenomectomy results in normalization of prolactin levels in 75-90% of cases ...
M, Jan, H, Dufour, T, Brue, P, Jaquet
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Journal of Endocrinological Investigation, 2011
Prolactinomas are the most common hormonally active pituitary tumors and are usually successfully treated with dopamine agonists. A small proportion, however, appears not to respond to such treatment and such cases are termed resistant prolactinomas. Resistance is generally defined as failure to achieve normoprolactinemia and inability to induce tumor ...
A. Beckers +4 more
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Prolactinomas are the most common hormonally active pituitary tumors and are usually successfully treated with dopamine agonists. A small proportion, however, appears not to respond to such treatment and such cases are termed resistant prolactinomas. Resistance is generally defined as failure to achieve normoprolactinemia and inability to induce tumor ...
A. Beckers +4 more
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Pituitary, 2005
Prolactinomas are the most frequent pituitary tumors. Treatment of infertility in such tumors usually is very successful. On the other hand, reports of pituitary tumor growth during pregnancy have been described since bromocriptine started to be used.
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Prolactinomas are the most frequent pituitary tumors. Treatment of infertility in such tumors usually is very successful. On the other hand, reports of pituitary tumor growth during pregnancy have been described since bromocriptine started to be used.
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Archives of Pediatrics & Adolescent Medicine, 1987
Sir .—I read with great interest the report by Huseman and colleagues 1 on a child with prolactinoma. The letter was extremely valuable in pointing the efficacy of bromocriptine therapy even in large tumors. It is reassuring to read that this conservative approach to treatment is as efficacious in children as it is in adults.
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Sir .—I read with great interest the report by Huseman and colleagues 1 on a child with prolactinoma. The letter was extremely valuable in pointing the efficacy of bromocriptine therapy even in large tumors. It is reassuring to read that this conservative approach to treatment is as efficacious in children as it is in adults.
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Headache, Hyperprolactinemia, and Prolactinomas
Obstetrical & Gynecological Survey, 1987The present study was undertaken to investigate whether headache in women with nonpuerperal hyperprolactinemia was related to elevated serum prolactin (PRL) levels or the presence of a PRL-secreting pituitary adenoma. The subjects were 469 women seen initially during the period of 1973 to 1979 at four clinical centers with the complaints of secondary ...
Peter M. Strebel +2 more
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Relation of RANKL and OPG Levels with Bone Resorption in Patients with Acromegaly and Prolactinoma
Hormone and Metabolic Research, 2018The objective of this study was to investigate the effect of hyperprolactinemia and high levels of insulin-like growth factor-I (IGF-I) on bone resorption and their relation with receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (
F. Ozer, S. Dağdelen, T. Erbaş
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The safety of treatments for prolactinomas
Expert Opinion on Drug Safety, 2016Prolactinomas are the most common hormone-secreting pituitary tumors, accounting for approximately 40% of all pituitary tumors. Infertility, gonadal and sexual dysfunction are usually the most relevant clinical features in both sexes.This review focuses on safety and tolerability of therapeutic approaches for prolactinomas.
AURIEMMA, RENATA SIMONA +3 more
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Best Practice & Research Clinical Endocrinology & Metabolism, 2011
Prolactinomas commonly cause infertility and treatment usually restores ovulation and fertility. The dopamine agonists are the preferred mode of treatment, with cabergoline generally being preferred to bromocriptine because of its higher therapeutic ratio.
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Prolactinomas commonly cause infertility and treatment usually restores ovulation and fertility. The dopamine agonists are the preferred mode of treatment, with cabergoline generally being preferred to bromocriptine because of its higher therapeutic ratio.
openaire +3 more sources