Aripiprazole use as a cause of dopamine agonist failure in the treatment of prolactinomas
Endocrine OncologyProlactinomas are the most common hypersecretory pituitary adenoma. The traditional first-line therapy is dopamine agonists (DAs), which are highly effective and tolerated in the majority of cases.
Edward Mignone +4 more
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Terguride stimulates locomotor activity at 2 months but not 10 months after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets [PDF]
, 1992 The mixed dopamine (DA) agonist/antagonist terguride acts as a DA antagonist on normosensitive receptors but shows DA agonistic properties at supersensitive DA receptors.
Horowski, R. +6 more
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Case Reports in Medicine, 2010 Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia. Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders.
Elvis Henrique Santos Andrade +3 more
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Alterações neuroendócrinas causadas por disruptores endócrinos: o exemplo do Bisfenol A [PDF]
, 2011 Los contaminantes ambientales, como los disruptores endocrinos,podrían provocar profundos cambios en los seres vivos. Aqui se analizan las alteraciones neuroendocrinas y reproductivas en mamíferos, incluyendo las descriptas en humanos, causadas por una ...
Bourguignon, Nadia +3 more
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A descriptive study to find possible correlation between MRI findings of pituitary gland and serum prolactin level [PDF]
, 2013 Objective: To explore equation, if any, between findings of magnetic resonance imaging of pituitary gland and serum prolactin level. Methods: The retrospective, descriptive study was conducted at the Department of Radiology, Aga Khan University Hospital,
Azeemuddin, Muhammad +2 more
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Mechanisms of Pituitary Tumorigenesis. Study of Angiogenic and Proliferation factors [PDF]
, 2013 Introduction and objectives: Angiogenesis is an essential process in tumor development. Nevertheless, discrepancies in the angiogenic pattern of pituitary tumors, in terms of hormonal phenotype, size or invasiveness have been found.
Becu, Damasia +6 more
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Secretory vesicle and cell surface markers for human endocrine pancreatic and pituiary tumors [PDF]
, 1992 Gratzl, Manfred +4 more
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Etiology, functional status and short term outcome of patients with pituitary lesions. An experience from a developing country [PDF]
, 2009 OBJECTIVE: To describe the etiology, functional status and short term outcome of patients with pituitary lesions (PL). METHODS: Brain or pituitary MRI reports of 3753 patients were analyzed for PL over the period of 2000 to 2007, done at the Aga Khan ...
Haq, Mansoor Ul +5 more
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Journal of NanobiotechnologyIntranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang +12 more
doaj +1 more source
Problems associated with the diagnosis and the prescribing of anti-psychotic medication in children and adolescents for psychiatric conditions, by non-psychiatric specialists [PDF]
, 2009 Aim: The objective of this study is to assess the accuracy of the diagnosis and appropriateness of antipsychotic medication prescribed to children and adolescents referred to child guidance clinic, and how many of these remained on the said medication ...
Camilleri, Nigel +2 more
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