Results 231 to 240 of about 111,060 (315)

Reduced folate receptor alpha (FOLR1) protein expression in fallopian tubes from premenopausal women: implications for the FOLR1 CDx assay for mirvetuximab‐soravtansine therapy

The Journal of Pathology: Clinical Research, Volume 12, Issue 3, May 2026.
Abstract Mirvetuximab‐soravtansine (MIRV‐S) is an antibody‐drug conjugate targeting folate receptor alpha (FOLR1). MIRV‐S is approved for the treatment of FOLR1‐positive, platinum‐resistant ovarian carcinoma. Patient eligibility is determined by immunohistochemistry (IHC) using a companion diagnostic (CDx) assay (FOLR1‐2.1, Ventana).
Annika Nasdala, Leonie D Kandt, Martin Radner, Nora Schaumann, Malte Gronewold, Pia Hillmann, Henriette Christgen, Jens Hachenberg, Elna Kuehnle, Christian Hartmann, Matthias Christgen   +10 more
wiley   +1 more source

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1021-1035, May 2026.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan, Naseebullah Kakar, Ainullah Kakar, Malte Spielmann, Sajid Malik   +4 more
wiley   +1 more source

Correction: Techniques in coloproctology-controversies in coloproctology: resection rectopexy is an underutilised procedure in the management of both symptomatic high-grade internal and external rectal prolapse. [PDF]

Tech Coloproctol
Bunni J, Courtney ED.
europepmc   +1 more source

Systemic immune dysregulation in patients experiencing urogynaecological mesh failure

BJUI Compass, Volume 7, Issue 5, May 2026.
Abstract Objectives This study aimed to investigate the systemic immune landscape in patients experiencing urogynaecological mesh failure. The use of urogynaecological mesh was paused in the UK following an independent safety review that found ~1 in 15 women required removal due to complications. However, the mechanisms underpinning mesh failure remain
Shannon Jamieson, Cameron R. Dougan, Eloise Rennie, Patrick Card, Sudarshan Nallappa, Karen Smith, David J. Deehan, Karen Brown, Catharien M. U. Hilkens, Christopher Harding   +9 more
wiley   +1 more source

Global Trends and Burden of Non-Neoplastic Gynecologic Diseases Among Women of Childbearing Age, 1990-2021: a GBD 2021 Analysis. [PDF]

Int J Womens Health
Sun Z, Liu H, Wang N, Sun P, Wu L, Xue E, Chen Y, Zhao J, Zeng K, Liu Y, Wan Z, Ye Y.   +11 more
europepmc   +1 more source

A Rare Case of P‐Null Phenotype Identified During Preoperative Screening

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 46‐year‐old woman scheduled for an elective total abdominal hysterectomy was incidentally found to have a rare P‐null (p) phenotype during routine preoperative testing. Although her ABO/Rh type was A positive, the antibody screen demonstrated strong pan‐reactivity with all panel cells, while the autocontrol was negative, indicating an ...
Alireza Abdollahi, Aysan Nozheh, Hassan Sohrabinia, Samaneh Salarvand   +3 more
wiley   +1 more source

Improving Diagnostic Accuracy for Surgical Pelvic Organ Prolapse: A Sequential Protocol Combining POP-Q Examination and Transperineal Ultrasound. [PDF]

J Clin Med
García-Mejido JA, Hurtado-Guijosa A, Fernández-Palacín A, Fernández-Palacín F, Bugatto F, Sainz-Bueno JA.   +5 more
europepmc   +1 more source

Reassessing Discordant Exudative Pleural Effusion in Heart Failure: A Rare Case of Occult Malignancy Uncovered by Post‐Thoracentesis Tension Pneumothorax

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pleural effusions can be manifestations of heart failure, pulmonary embolism, infection, and malignancy. Symptom assessment, imaging, and pleural fluid analysis serve as key determinants in guiding clinical management. We present the case of a 75‐year‐old woman with a history of heart failure who developed worsening dyspnea and lower extremity
Christ Ordookhanian, Ryan Feld Amidon, Sameh Hanna, Benjamin Tabibian   +3 more
wiley   +1 more source

Efficacy of OB balloon tamponade in cesarean delivery for placenta previa and low-lying placenta: a retrospective comparative study. [PDF]

BMC Pregnancy Childbirth
Yasoshima I, Hoshiba N, Iizuka T, Kagami K, Tanaka M, Abiko K.   +5 more
europepmc   +1 more source

The Association of Childbirth Preparation Classes with Labor Pain, Labor Duration, and Neonatal Outcomes in the Northeast of Iran During 2018–2019: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Childbirth preparation classes aim to equip expectant parents with knowledge and skills for a smoother labor process. This study evaluated their effects on labor pain, duration, and neonatal outcomes. Methods This retrospective cohort study involved 240 primiparous women, with 120 attending at least four classes and 120 not
Fatemeh Yahyavi Koochaksaraei, Masoumeh Alijanpour, Fatemeh Nasiri‐Amiri, Shabnam Omidvar, Shanaz Barat, Hemmat gholinia‐ahangar   +5 more
wiley   +1 more source