Results 141 to 150 of about 12,181 (285)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles. [PDF]
J Thromb Thrombolysis, 2021 Becker RC +3 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Unique Metabolic Contexts Sensitize Cancer Cells and Discriminate between Glycolytic Tumor Types. [PDF]
Cancers (Basel), 2023 Chacon-Barahona JA +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
, 2018 George Orwell was one of the most significant literary figures on the left in the twentieth century. While titles such as 1984, Animal Farm and Homage to Catalonia are still rightly regarded as modern classics, his own politics are less well understood. Hope Lies in the Proles offers a sympathetic yet critical account of Orwell's political thinking and
openaire +2 more sources
A Field Collection of Indigenous Grapevines as a Valuable Repository for Applied Research. [PDF]
Plants (Basel), 2022 Shecori S +7 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Acta Scientiarum. Health Sciences, 2007 O estudo teve como objetivo descrever e analisar características individuais e familiares das crianças e características do serviço de saúde e suas relações com a situação vacinal para diferentes tipos de vacinas e doses.
Ana Cláudia Molina +3 more
doaj
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source