Results 151 to 160 of about 12,181 (285)

Prole(taries) al borde del tiempo

open access: yesMariCorners: Revista de Estudios Interdisciplinares LGTBIA+ y queer
La ficción especulativa feminista y queer opera como un laboratorio político donde disputar una organización alternativa de los cuidados, más allá de las instituciones del capitalismo racial. Tal es el caso de las futuridades ficticias imaginadas por Marge Piercy en Woman on the Edge of Time (1976) y por ME.
openaire   +1 more source

Efficacy of Prolotherapy in Temporomandibular Joint Disorders: An Exploratory Study. [PDF]

open access: yesJ Maxillofac Oral Surg, 2021
Dasukil S, Shetty SK, Arora G, Degala S.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Parentage Atlas of Italian Grapevine Varieties as Inferred From SNP Genotyping. [PDF]

open access: yesFront Plant Sci, 2020
D'Onofrio C   +11 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Seed morphometrics unravels the evolutionary history of grapevine in France. [PDF]

open access: yesSci Rep
Bouby L   +31 more
europepmc   +1 more source

[Asthma control from primary care with a gender and family focus]. [PDF]

open access: yesAten Primaria, 2020
Duarte Ayala RE   +3 more
europepmc   +1 more source

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