Results 121 to 130 of about 2,929,257 (346)

Calcium Homeostasis Is Involved in the Modulation of Gene Expression by MSL2 in Imbalanced Genomes

Cells
Aneuploidy is highly detrimental to organisms due to genomic imbalance. However, the influence of parental unbalanced genome conditions on gene expression of their offspring remains unclear, particularly in animals.
Ruixue Wang, Shuai Zhang, Haizhu Qi, Liuqing Wang, Youjun Wang, Lin Sun   +5 more
doaj   +1 more source

The Measurement of Proliferation in Tissue Cultures by Enumeration of Cell Nuclei [PDF]

, 1951
Katherine K. Sanford, Wilton R. Earle, Virginia J. Evans, Helen K. Waltz, John E. Shannon   +4 more
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

β-Glucuronidase and cell proliferation [PDF]

, 1948
G. A. Levvy, Lynda M. H. Kerr, J. G. Campbell   +2 more
openalex   +1 more source

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Science, 2009
M. V. Vander Heiden, L. Cantley, C. Thompson   +2 more
semanticscholar   +1 more source

An eIF for proliferation

The Journal of Cell Biology, 2008
![Graphic][1] Breast cancer cells fill with autophagosomes (green) when eIF4GI is silenced. Proliferation gets its own translation initiation factor, based on findings from [Ramirez-Valle et al.][2] The results help explain why that eIF is commonly overexpressed in breast ...
openaire   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Ueber Proliferation, Metaplasie und Resorption des Knochengewebes [PDF]

, 1878
Ernst Ziegler
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

EFFECT OF LIVER AND PITUITARY DIGESTS ON THE PROLIFERATION OF SARCOMATOUS FIBROBLASTS OF THE RAT [PDF]

, 1928
Lillian E. Baker, Alexis Carrel
openalex   +1 more source