Results 131 to 140 of about 3,456,235 (361)
SCFSAP controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana [PDF]
, 2016 Control of organ size by cell proliferation and growth is a fundamental process, but the mechanisms that determine the final size of organs are largely elusive in plants. We have previously revealed that the ubiquitin receptor DA1 regulates organ size by
Gonzalez Sanchez, Nathalie +7 more
core +3 more sources
Dendritic cell MST1 inhibits Th17 differentiation
Nature Communications, 2017 The differentiation of Th17 cells is central to infection and autoimmunity. Here, the authors show that expression of MST1 by dendritic cells limits IL-6 production and thereby controls Th17 differentiation in immunity to fungal infection and ...
Chunxiao Li +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Cell Reports, 2022 Summary: The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus; however, our understanding of the physiological roles of PT in sperm is very limited.
Xiao-Zhen Zhang +4 more
doaj
Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division
eLife, 2017 Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g.
Jennifer J Banerjee +5 more
doaj +1 more source
Understanding Hepatitis B Virus Infection through Hepatocyte Proliferation and Capsid Recycling [PDF]
arXivProliferation of uninfected as well as infected hepatocytes and recycling of DNA-containing capsids are two major mechanisms playing significant roles in the clearance of hepatitis B virus (HBV) infection. In this study, the temporal dynamics of this infection are investigated through two in silico bio-mathematical models considering both ...
arxiv
Spectral bounds for percolation on directed and undirected graphs [PDF]
arXiv, 2015 We give several algebraic bounds for percolation on directed and undirected graphs: proliferation of strongly-connected clusters, proliferation of in- and out-clusters, and the transition associated with the number of giant components.
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source