Results 131 to 140 of about 2,929,257 (346)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Proliferation of Limbal Melanoblasts into the Cornea in Response to a Corneal Lesion : An Experimental Note [PDF]

, 1952
I. C. Michaelson
openalex   +1 more source

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

Cell Metabolism, 2008
R. Deberardinis, J. Lum, G. Hatzivassiliou, C. Thompson   +3 more
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Inflammasomes and their roles in autoimmune diseases

Rheumatology & Autoimmunity
Autoimmune diseases are immune disorders in which the immune system mistakenly targets and attacks the normal cells, tissues, and organs of the patients. The etiology of autoimmune diseases is complex and multifactorial.
Minghui Pan, Jie Yang, Zhengfan Jiang
doaj   +1 more source

CELLULAR PROLIFERATION IN THE MOUSE AS REVEALED BY AUTORADIOGRAPHY WITH TRITIATED THYMIDINE

, 1958
Walter L. Hughes, V.P. Bond, G. Brecher, E. P. Cronkite, Robert B. Painter, Henry Quastler, F.G. Sherman   +6 more
openalex   +1 more source

A Proliferation of the Sorghum Spikelets. [PDF]

, 1942
SANKARA AYYAR
openalex   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Relationship of interstitial pneumonia honeycombing and atypical epithelial proliferation to cancer of the lung [PDF]

, 1965
Edward C. Meyer, Averill A. Liebow
openalex   +1 more source