Results 161 to 170 of about 2,619,152 (303)

Eco-Evolutionary Dynamics of Proliferation Heterogeneity: A Phenotype-Structured Model for Tumor Growth and Treatment Response. [PDF]

Bull Math Biol
Schmalenstroer L, Chen H, Rockne RC, Farahpour F.   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Long-Term Structural and Functional Restoration of the Retina After Inverted Internal Limiting Membrane Flap Surgery for Idiopathic Full-Thickness Macular Holes. [PDF]

Diagnostics (Basel)
Lorenc O, Safranow K, Machalińska A.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Two opposite effects of desmoglein 3 on the growth of oral squamous cell carcinoma between anchorage -dependent and -independent conditions. [PDF]

PLoS One
Inada J, Minabe M, Akiyama Y, Higa K, Nomura T, Kouno M.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Transcriptome and Functional Analysis Uncover the Role of ADCY5 in Bovine Adipogenesis. [PDF]

Anim Genet
Wei X, Shan X, Yang L, Zhao X, Ma Y, Zhang P, Xu Y, Hao R.   +7 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Proliferating trichilemmal tumor

Anais Brasileiros de Dermatologia, 2023
Andrea Abê Pereira, Jéssica Lüders Bueno, Ana Letícia Boff, Paulo Ricardo Martins Souza   +3 more
openaire   +4 more sources

Increased Epithelial Cell Proliferation in Nasal Polyps

, 2009
Background and Purpose: The mucociliary function of the sinonasal mucosa is an innate defense mechanism of the human nasal airway. Epithelial cell proliferation is required for cell renewal and repair of the sinonasal mucosa.
SHIU, MING-JE;SHUN, CHIA-TUNG;LIU, CHIA-MING, 許明哲;孫家棟;劉嘉銘   +1 more
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