Results 221 to 230 of about 3,711,169 (334)

Fascin Drives Breast Cancer Cell Proliferation Partly by Modulating the Cell Cycle Checkpoint Regulators of the G1-S Phase. [PDF]

Cells
Ghebeh H, Al-Nasrallah HK, Elfoly M, Aldossry A, Tulbah A, Al-Tweigeri T, Al-Alwan M.   +6 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

EIF5A1 promotes epithelial ovarian cancer proliferation and progression

, 2018
Jing Zhang, Xiao Li, Xiaorui Liu, Fu‐Ju Tian, Weihong Zeng, Xiaowei Xi, Yi Lin   +6 more
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression. [PDF]

Front Mol Biosci
Ke Q, Li Z, Fan L, Li N, Sun L, Zhao H, Song T.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension. [PDF]

Front Cell Dev Biol
Fan T, Li L, Wang Y, Lin M, Wu F.
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Trophoblast Function in Preeclampsia: Decoding the Mechanistic Roles of Coding and Non-Coding Genes. [PDF]

Int J Mol Sci
Oancea M, Strilciuc S, Zanoaga O, Ciocan C, Malutan A, Păunescu I, Boitor D, Braicu C, Mihu D.   +8 more
europepmc   +1 more source

Ductular Proliferation

Gastroenterology, 1965
openaire   +2 more sources