Results 231 to 240 of about 2,929,257 (346)

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

SOX9: an important factor in regulating breast cancer. [PDF]

Eur J Med Res
Wang Y, Chu J, Huang L, Qian M.
europepmc   +1 more source

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets.

Seminars in Cancer Biology, 2015
M. Feitelson, A. Arzumanyan, Rob J. Kulathinal, S. Blain, R. Holcombe, J. Mahajna, M. Marino, M. Martínez‐Chantar, R. Nawroth, I. Sánchez-García, D. Sharma, N. Saxena, Neetu Singh, P. Vlachostergios, Shanchun Guo, K. Honoki, H. Fujii, A. Georgakilas, A. Bilsland, A. Amedei, E. Niccolai, A. Amin, S. Ashraf, Chandra S Boosani, G. Guha, M. Ciriolo, K. Aquilano, Sophie S. Chen, S. Mohammed, A. Azmi, D. Bhakta, D. Halicka, W. Keith, S. Nowsheen   +33 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Circular RNAs: key regulators of paclitaxel sensitivity and resistance in cancer. [PDF]

Eur J Med Res
Tajik Z, Ghafouri-Fard S.
europepmc   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

CircIDH2 Modulates Porcine Adipogenesis via the miR-193a-5p/<i>RASGRP</i>4 Axis: Implications for ceRNA-Mediated Regulation of Fat Deposition. [PDF]

Cells
Li M, Chen J, Bao W, Ma S, Wen M, Han Y, Zhang W, Yang Y, Guo X, Li B.   +9 more
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

The effect of hyperbaric oxygen and platelet-rich plasma treatments on the adipogenic C2C12 myoblast cell line. [PDF]

BMC Musculoskelet Disord
Chiu JC, Chen P, Lei KF, Chang GJ, Chen SC, Higashikawa R, Chan YS.   +6 more
europepmc   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source