Results 31 to 40 of about 27,228 (223)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Spontaneous Closure of a Full-Thickness Macular Hole Associated with Proliferative Diabetic Retinopathy and Persistent Vitreomacular Traction

Case Reports in Ophthalmology, 2016
Diabetic retinopathy worsens the prognosis of macular holes compared to those of idiopathic etiology. While spontaneous closure of idiopathic macular holes is a well-documented phenomenon, spontaneous closure of macular holes associated with ...
Benjamin J. Reinherz, Jeffrey S. Rubin
doaj   +1 more source

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

Animal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu, Shurui Huo, Wenguang Wang, Na Li, Qingwei Zeng, Xiaomei Sun, Jiejie Dai, Pinfen Tong, Yuanyuan Han, Ling Zhao, Caixia Lu   +10 more
wiley   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Proliferative Diabetic Retinopathy

På verdensplan lever over 828 millioner mennesker med diabetes. Diabetisknethindesygdom er en velkendt komplikation til diabetes og udvikles hos mange patienter i forskellig grad efter længere tid med forhøjet blodsukker. Diabetisknethindesygdom forløber over fem stadier startende med ingen nethindeforandringer (niveau 0), minimale nethindeforandringer
Emily D. Cole, Nadia K. Waheed, Jay S. Duker   +2 more
  +6 more sources

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Demographics, Awareness and Pattern of Diabetic Retinopathy among Diabetic Patients

Journal of Nobel Medical College
Background: Diabetic retinopathy is one of the emerging causes of blindness in developing countries. This study was carried out among diabetic patients to determine the demographics, severity of diabetic retinopathy and also to assess the level of ...
Anjila Basnet, Raghunandan Byanju, Samir Thapa, Sanjit Kumar Shah, Suman Simkhada   +4 more
doaj   +1 more source

ND:YAG laser for preretinal hemorrhage in diabetic retinopathy

American Journal of Ophthalmology Case Reports, 2018
Purpose: To present fundus images of a case with severe preretinal hemorrhage in diabetic retinopathy that was treated with posterior hyaloidotomy with an Nd:YAG laser.
Dimitrios Karagiannis, Georgios A. Kontadakis, Declan Flanagan   +2 more
doaj   +1 more source

An Alternative Aproach of Exercise Prescription for Type 2 Diabetes Control in Time and Space Restrictions

Chronic Diseases and Translational Medicine, EarlyView.
Continuum of physical behavior changes and important questions about exercise prescription approach in the diabetes context. ABSTRACT Although physical exercise is widely recognized for its role in glycemic control and overall health, population characteristics such as comorbidities, sedentary behavior, disease‐related complications, and socioeconomic ...
Rodrigo Sudatti Delevatti, Samara Nickel Rodrigues, Cristine Lima Alberton   +2 more
wiley   +1 more source