Results 1 to 10 of about 7,344 (158)

Leveraging AAV1-Rac1T17N to prevent experimental proliferative vitreoretinopathy [PDF]

Journal of Translational Medicine
Background Platelet-derived growth factor receptor β (PDGFRβ) is the principal PDGFR isoform in retinal pigment epithelial (RPE) cells from the epiretinal membranes of patients with proliferative vitreoretinopathy (PVR).
Duo Li, Minli Linghu, Jisen Tang, Gukun Yang, Chuanwu Li, Hang Yao, Hetian Lei, Yikeng Huang, Xionggao Huang   +8 more
doaj   +2 more sources

p21CIP/WAF1 saRNA inhibits proliferative vitreoretinopathy in a rabbit model.

PLoS ONE, 2023
PurposeProliferative vitreoretinopathy (PVR) is a disease process resulting from proliferation of retinal pigment epithelial (RPE) cells in the vitreous and periretinal area, leading to periretinal membrane formation and traction and eventually to ...
Qi Zhang, Yangchen Guo, Moorim Kang, Wei-Hsiang Lin, Jian-Cheng Wu, Ying Yu, Long-Cheng Li, Aimin Sang   +7 more
doaj   +4 more sources

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice [PDF]

Nature Communications
Proliferative vitreoretinopathy is a vision-threatening response to penetrating ocular injury, for which there is no satisfactory treatment. In this disorder, retinal pigment epithelial cells, abandon their attachment to Bruch’s membrane on the scleral ...
Min Luo, Dena Almeida, Valentina Dallacasagrande, Nadia Hedhli, Mrinali Gupta, Donald J. D’Amico, Szilárd Kiss, Katherine A. Hajjar   +7 more
doaj   +2 more sources

Proliferative vitreoretinopathy and its relationship with inflammatory serum biomarkers [PDF]

International Journal of Ophthalmology
AIM: To analyze if a relationship between levels of inflammatory serum biomarkers and severity of primary proliferative vitreoretinopathy (PVR) exists. METHODS: A retrospective case-control study.
Victor Alejandro Martinez Pacheco, Sergio Rojas Juarez, Braulio Hernan Velasco Sepulveda, Abel Ramirez Estudillo   +3 more
doaj   +2 more sources

Effects of repeated intra-silicone oil injections of methotrexate on proliferative vitreoretinopathy grade C: a multicenter randomized controlled trial [PDF]

Scientific Reports
In this randomized controlled trial, we assessed the effects of three consecutive intra-silicone oil (SO) injections of methotrexate (MTX) on the outcomes of surgery for proliferative vitreoretinopathy grade C (PVR-C).
Ramin Nourinia, Sare Safi, Mehrad Mohammadpour, Hamid Riazi-Esfahani, Mohammad Reza Ansari Astaneh, Khalil Ghasemi Falavarjani, Alireza Ramezani, Saeed Karimi, Sahba Fekri, Nazanin Ebrahimiadib, Elias Khalili Pour, Homayoun Nikkhah, Nasser Shoeibi, Narges Hassanpoor, Maryam Hosseini, Mojtaba Abrishami, Fatemeh Abdi, Anoushiravan Rahimi, Mohammad Hossein Jabbarpoor Bonyadi, Siamak Moradian, Sina Khosravi Mirzaei, Hamid Safi, Pasha Anvari, Kaveh Fadakar, Masoud Mirghorbani, Niloufar Mohammadbagheri, Firouze Hatami, Bahareh Kheiri, Mehdi Yaseri, Zahra Khorrami, Hamid Ahmadieh   +30 more
doaj   +2 more sources

Regulation and mechanism of chloride channels in proliferative vitreoretinopathy. [PDF]

Medicine (Baltimore)
Wen W, Xu D, Jiang M, Liu Y, Li X, Sun L.   +5 more
europepmc   +2 more sources

Risk factors for failure after primary vitrectomy with no scleral buckling for rhegmatogenous retinal detachment [PDF]

Revista Brasileira de Oftalmologia, 2023
Objective To assess pre-operative conditions that could influence primary anatomical success rate in a cohort of patients with rhegmatogenous retinal detachments (RRD) treated with primary vitrectomy and no scleral buckling.
Mariano Iros, Juan Manuel Lopez, Nicolás Crim, Evangelina Espósito, Julio A. Urrets-Zavalía   +4 more
doaj   +1 more source

Intraocular use of methotrexate (MTX) for the treatment of proliferative vitreoretinopathy (PVR) in congenital aniridia (CI) and a possible link to aniridia fibrosis syndrome (AFS) treatment. [PDF]

Am J Ophthalmol Case Rep
Ambati NR, Riemann CD.
europepmc   +2 more sources

Development and validation of the Artificial Intelligence-Proliferative Vitreoretinopathy (AI-PVR) Insight system for deep learning-based diagnosis and postoperative risk prediction in proliferative vitreoretinopathy using multimodal fundus imaging. [PDF]

Quant Imaging Med Surg
Gan F, Cao J, Fan H, Qin W, Li X, Wan Q, Liu T, Liu K, You Z.   +8 more
europepmc   +2 more sources

Proliferative vitreoretinopathy and it’s prevention in cases of extensive penetrating wounds of the sclera

Офтальмохирургия, 2023
Relevance. Currently, there is no single algorithm for the management of patients with extensive penetrating wounds of the sclera, and the frequency of proliferative vitreoretinopathy, leading to adverse outcomes, is very high. Purpose.
S.S. Shamkin, S.N. Subbotina
doaj   +1 more source