Results 41 to 50 of about 146,300 (194)

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical ...
Koen A. van Overdam, J. Sebag
wiley   +1 more source

Impact of retinal break location on surgical outcomes in primary uncomplicated rhegmatogenous retinal detachment: Superior versus inferior breaks

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To compare the anatomical and functional outcomes of pars plana vitrectomy (PPV) for primary uncomplicated rhegmatogenous retinal detachment (RRD) with superior versus inferior retinal breaks. Methods This retrospective study included 675 eyes of 675 patients, of which 476 had exclusively superior breaks and 199 had at least one ...
Ioanna Dimakopoulou   +7 more
wiley   +1 more source

Nearly doubled incidence of surgically treated primary rhegmatogenous retinal detachment in Southern Sweden, 2011–2025

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the incidence of surgically treated primary rhegmatogenous retinal detachment (RRD) in Southern Sweden between 2011 and 2025, and to examine whether demographic change or risk factor trends account for any change in incidence.
Pernilla Rosenquist, Joakim Thylefors
wiley   +1 more source

CHARACTERISTICS OF RETINAL DETACHMENT PATIENTS WITH PROLIFERATIVE VITREORETINOPATHY AT Dr. SOETOMO GENERAL ACADEMIC HOSPITAL

open access: yesIJRETINA (International Journal of Retina), 2019
Introduction: The aim of this study is to evaluate the incidence and characteristics of retinal detachment patients with proliferative vitreoretinopathy.
Ifan Romadhon Lukmana   +7 more
doaj   +1 more source

Techniques for subretinal injections in animals

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Grade of proliferative vitreoretinopathy (PVR) and macular status of eyes with RRD.

open access: yes, 2013
Grade of proliferative vitreoretinopathy (PVR) and macular status of eyes with RRD.
Tsedeke Asaminew (463822)   +3 more
core   +1 more source

Experimental Models to Study Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy

open access: yes, 2023
Proliferative vitreoretinal diseases (PVDs) encompass proliferative vitreoretinopathy (PVR), epiretinal membranes, and proliferative diabetic retinopathy.
François Willermain   +5 more
core   +1 more source

A multicenter study on rates and risk factors of proliferative vitreoretinopathy in a low-income economy [PDF]

open access: yesPLoS ONE
Ogugua Ndubuisi Okonkwo   +8 more
doaj   +2 more sources

A Practical Guide to Optimal Adaptive Two‐Stage Designs for Various Endpoint Types

open access: yesPharmaceutical Statistics, Volume 25, Issue 6, November/December 2026.
ABSTRACT Adaptive designs are frequently used to adjust sample sizes based on interim data, ensuring reliable conclusions while protecting resources. To maximize trial efficiency, design parameters can be optimized to minimize an objective function (e.g., the expected sample size) while rigorously controlling overall error rates or further operating ...
Nico Bruder   +3 more
wiley   +1 more source

Three hundred sixty‐degree prophylactic laser retinopexy versus focal laser during rhegmatogenous retinal detachment repair: A systematic review and meta‐analysis

open access: yesActa Ophthalmologica, Volume 104, Issue 7, Page 731-741, November 2026.
Abstract Purpose To compare the anatomic, functional and safety outcomes of intra‐operative 360‐degree prophylactic laser retinopexy versus focal laser retinopexy during pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) and to assess the certainty of evidence.
Luke Yaldo   +5 more
wiley   +1 more source

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