Results 61 to 70 of about 6,081 (166)

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Hybrid wide-angle viewing-endoscopic vitrectomy using a 3D visualization system

Clinical Ophthalmology, 2018
Mihori Kita, Yuki Mori, Sachiyo Hama Department of Ophthalmology, National Organization Kyoto Medical Center, Kyoto, Japan Purpose: To introduce a hybrid wide-angle viewing-endoscopic vitrectomy, which we have reported, using a 3D visualization system ...
Kita M, Mori Y, Hama S
doaj  

Giant Retinal Hole and Retinal Detachment following Exercise Band Injury: A Case Report

Case Reports in Ophthalmology
Introduction: Elastic resistance bands have been widely adopted in exercise programs for all age-groups. However, increased use of these resistance bands has been associated with a rise in blunt facial and ocular injuries, of which severe ones
Justin Chen, Michael Ying Zhao, Landon James Rohowetz, Harry W. Flynn Jr.   +3 more
doaj   +1 more source

CHARACTERISTICS OF RETINAL DETACHMENT PATIENTS WITH PROLIFERATIVE VITREORETINOPATHY AT Dr. SOETOMO GENERAL ACADEMIC HOSPITAL

IJRETINA (International Journal of Retina), 2019
Introduction: The aim of this study is to evaluate the incidence and characteristics of retinal detachment patients with proliferative vitreoretinopathy.
Ifan Romadhon Lukmana, Sauli Ari Widjaja, Wimbo Sasono, Muhammad Firmansjah, Ima Yustiarini, Ady Dwi Prakosa, Moestidjab Moestidjab, Gatut Suhendro   +7 more
doaj   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, Volume 13, Issue 2, 9 January 2026.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Proliferative vitreoretinopathy: current and emerging treatments

Clinical Ophthalmology, 2012
Ama Sadaka,1 Gian Paolo Giuliari2,31Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; 2Centro de Cirugía Oftalmológica (CECOF), Caracas, Venezuela; 3Department of Ophthalmology, Domingo Luciani ...
Sadaka A, Giuliari GP
doaj  

Novel Vitreous Substitutes in Animal and Human Models: A Systematic Review

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Vitreous substitutes are crucial adjuncts during vitreoretinal surgery for retinal detachment, macular holes, and vitreous hemorrhage. However, current vitreous substitutes pose limitations, including but not limited to their postoperative decrease in visual sharpness, nonfavorable refractive indices, and complications such as glaucoma ...
Danielle Solish, Lia Huo, Tony Shicheng Jin, Brandon Hall, Eunice L. You, Marko M. Popovic, Adam Forman, Molly Shoichet, Robert Devenyi, Brian G. Ballios, Peng Yan, Baisakhi Banerjee   +11 more
wiley   +1 more source

Relaxing retinectomy and autologous retinal transplant for complex retinal detachment with macular hole: a case series

International Journal of Retina and Vitreous
Background To describe the surgical techniques for transplantation of an autologous retinal graft in cases of chronic retinal detachment with proliferative vitreoretinopathy and full-thickness macular hole.
Rami Madani, Armin Wolf, Jad Madani, Michael F. Ward, Matthew Cohen, Ferris Bayasi, Tarek Alasil   +6 more
doaj   +1 more source

Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.

PLoS ONE, 2020
Proliferative vitreoretinopathy (PVR) is a progressive disease that develops in a subset of patients who undergo surgery for retinal detachment repair, and results in significant vision loss.
Alison M Heffer, Victor Wang, Richard T Libby, Steven E Feldon, Collynn F Woeller, Ajay E Kuriyan   +5 more
doaj   +1 more source

Minimally Invasive Segmental Scleral Buckle as Primary Surgery for the Repair of Rhegmatogenous Retinal Detachment: A Descriptive Case Series Study

Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.
Introduction The scleral buckling (SB) or encircling buckle technique has been employed in the management of rhegmatogenous retinal detachment (RRD). While encircling buckle technique offers substantial assistance in managing RRD, particularly for cases involving numerous breaks or extensive detachments, this procedure is time‐consuming and associated ...
Supanji Supanji, Dewi Fathin Romdhoniyyah, Hifdza Faza Felisha, Felicia Widyaputri, Tiara Putri Utami, Erin Arsianti, Mohammad Eko Prayogo, Firman Setya Wardhana, Muhammad Bayu Sasongko, Karuna Sharma   +9 more
wiley   +1 more source