Results 261 to 270 of about 195,829 (321)

Chronic Effect of Cadmium on <SUP>3</SUP>H-Proline Metabolism. 1. Urinary Excretion and Retention of <SUP>3</SUP>H-Proline repeatedly injected into Rats (Regular Presentations) (Proceedings of the 8th Symposium on Environmental Pollutants and Toxicology)

, 1982
Michiko Sakamoto, Keiko Kawahara, Takashi Kushihata   +2 more
openalex   +2 more sources

Media‐Dependent Growth, Stress Responses, and Metal Accumulation Patterns in Azolla imbricata (Roxb.) Nakai Exposed to As, Cd, Cu, Pb, and Zn: Individual and Combination Effects (Synergistic, Antagonistic, and Additive)

Environmental Toxicology, EarlyView.
ABSTRACT In this study, we examined metal accumulation and biochemical responses of Azolla imbricata (Roxb.) Nakai exposed to water medium (WM) and nutrient medium (NM) under single and combined (co‐exposure) treatments with five metals (As, Cd, Cu, Pb, and Zn) at 10% environmentally relevant concentrations.
Sung‐Chul Hong, Je‐Sung Park, Seong‐Ho Jang, Eun‐Sang Jung, Byung‐Gil Jung, Anisa Dea Novianti, Velmurugan Palanivel, Young‐Chae Song, Arpita Kumari, Geetha Parameswaran, Sivakumar Subpiramaniyam   +10 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source

Extreme Silk Toughness in Caerostris Spiders Is Limited to Adult Females

Integrative Zoology, EarlyView.
We ask whether species with exceptionally tough silk, like Caerostris bark spiders, show different developmental patterns in silk toughness between ontogenetic stages and sexes. We found that only large females produce exceptionally tough silk with higher initial stiffness, while juvenile females as well as adult and juvenile males produce inferior ...
Matjaž Gregorič, Kuang‐Ping Yu, Jeremia Ravelojaona, Todd A. Blackledge, Matjaž Kuntner   +4 more
wiley   +1 more source

Proline metabolism reprogramming in cancer reveals the regulation of PRODH/POX as target

Yuxuan Zhou, Ciqin Li, Dingyuan Bai, Lingjie Jing, Leng Han, Cheng Guo, Quanjun Yang   +6 more
openalex   +1 more source

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

Integrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu, Xibao Wang, Yongquan Shang, Yao Chen, Haotian Cai, Tian Xia, Qinguo Wei, Weilai Sha, Honghai Zhang   +8 more
wiley   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source