Results 1 to 10 of about 253,684 (257)
Continuous proline catalysis via leaching of solid proline [PDF]
Beilstein Journal of Organic Chemistry, 2011 Herein, we demonstrate that a homogeneous catalyst can be prepared continuously via reaction with a packed-bed of a catalyst precursor. Specifically, we perform continuous proline catalyzed α-aminoxylations using a packed-bed of L-proline.
Suzanne M. Opalka +2 more
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A mechanochemical approach to access the proline–proline diketopiperazine framework [PDF]
Beilstein Journal of Organic Chemistry, 2017 Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides ...
Nicolas Pétry +9 more
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Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline [PDF]
Molecules, 2017 Proline utilization A (PutA) is a bifunctional flavoenzyme that catalyzes the two-step oxidation of l-proline to l-glutamate using spatially separated proline dehydrogenase (PRODH) and l-glutamate-γ-semialdehyde dehydrogenase (GSALDH) active sites ...
David A. Korasick +4 more
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Sources of superoxide/H2O2 during mitochondrial proline oxidation
Redox Biology, 2014 p53 Inducible gene 6 (PIG6) encodes mitochondrial proline dehydrogenase (PRODH) and is up-regulated several fold upon p53 activation. Proline dehydrogenase is proposed to generate radicals that contribute to cancer cell apoptosis.
Renata L S Gonçalves +2 more
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Connecting proline metabolism and signaling pathways in plant senescence
Frontiers in Plant Science, 2015 The amino acid proline has a unique biological role in stress adaptation. Proline metabolism is manipulated under stress by multiple and complex regulatory pathways and can profoundly influence cell death and survival in microorganisms, plants, and ...
Lu Zhang, Donald F Becker
exaly +3 more sources
Biomolecules, 2021 L-proline (proline) is a key regulator of embryogenesis, placental development, and fetal growth. However, the underlying mechanisms that support the beneficial effects of proline are largely unknown.
Ning Liu +7 more
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Current Plant Biology, 2023 Proline/P5C cycle between mitochondria and cytosol, play important roles in energy supply and ROS (Reactive oxygen species) generation in mammalian cell.
Wenhan Ying +6 more
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The sodium/proline transporter PutP of Helicobacter pylori. [PDF]
PLoS ONE, 2013 Helicobacter pylori is cause of chronic gastritis, duodenal ulcer and gastric carcinoma in humans. L-proline is a preferred energy source of the microaerophilic bacterium. Previous analyses revealed that HpputP and HpputA, the genes that are predicted to
Araceli Rivera-Ordaz +8 more
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Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome. [PDF]
PLoS ONE, 2013 Proline is an anomalous amino acid. Its nitrogen atom is covalently locked within a ring, thus it is the only proteinogenic amino acid with a constrained phi angle.
Alexander A Morgan, Edward Rubenstein
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Enzymatic production of trans‐4‐hydroxy‐l‐proline by proline 4‐hydroxylase
Microbial Biotechnology, 2021 Summary Trans‐4‐hydroxy‐l‐proline (Hyp) is a useful chiral building block for production of many nutritional supplements and pharmaceuticals. However, it is still challenging for industrial production of Hyp due to heavy environmental pollution and low ...
Xiulai Chen +4 more
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