Results 31 to 40 of about 329,298 (293)

Mitochondrial dynamics links PINCH-1 signaling to proline metabolic reprogramming and tumor growth

open access: yesCell Stress, 2020
Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants to animals. In bacteria and plants, proline is known to accrue in response to osmotic and other
Ling Guo, Chuanyue Wu
doaj   +1 more source

Scientific Opinion on the substantiation of health claims related to isoleucine‐proline‐proline (IPP) and valine‐proline‐proline (VPP) and maintenance of normal blood pressure (ID 661, 1831, 1832, 2891, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

open access: yesEFSA Journal, 2012
Following a request from the European Commission, pursuant to Article 13.1 of Regulation (EC) No 1924/2006, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a health claim related to isoleucine‐proline ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae

open access: yesMicrobial Cell, 2019
In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes.
Yukio Mukai   +7 more
doaj   +1 more source

An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

open access: yesFrontiers in Molecular Biosciences, 2021
Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain.
Juan Alcantara   +7 more
doaj   +1 more source

The regulatory mechanisms of proline and hydroxyproline metabolism: Recent advances in perspective

open access: yesFrontiers in Oncology, 2023
For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily synthesized from glutamine.
James M. Phang
doaj   +1 more source

Effect of water stress on morphological traits, mucilage percentage and yield of Alyssum homolocarpum [PDF]

open access: yesDesert, 2021
A pot experiment was carried out to study the impacts of water stress upon physiological and biochemical properties as well as seed yield and components yield of Alyssum homolocarpum.
M. Zaferanieh, B. Mahdavi
doaj   +1 more source

Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose [PDF]

open access: yes, 2018
Chiral recognition remains a major challenge in the area of molecular receptor design. With this research, we set out to explore the use of proline-based receptors for chiral recognition.
Zhang, Miao   +17 more
core   +1 more source

Proline transport inhibitors trigger differential responses in Trypanosoma cruzi growth inhibition [PDF]

open access: yes, 2021
Background: Proline is a fundamental amino acid for Trypanosoma cruzi, the etiological agent of Chagas disease. Proline is mainly incorporated from the extracellular medium by amino acid transport systems.
Lucas , Pagura   +5 more
core   +2 more sources

EFFECTS OF SALT STRESS ON SOME GROWTH PARAMETERS AND BIOCHEMICAL CHANGES IN BEAN (Phaseolus vulgaris L.)

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2022
Salinity is one of the most important abiotic stresses that affect plant cell metabolism and reduce plant productivity. In the study, some growth and biochemical characteristics of two different types of dwarf and lantern beans were investigated.
Mustafa Çirka   +3 more
doaj   +1 more source

Stomatitis Healing via Hydrogels Comprising Proline, Carboxyvinyl Polymer, and Water

open access: yesGels
Chemotherapy using anticancer agents and radiotherapy of cancers frequently induce the development of stomatitis as a side effect. In the present study, hydrogels for effective stomatitis healing under anticancer drug administration were developed using ...
Raichi Hanaki   +4 more
doaj   +1 more source

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