Proline-rich region of non-muscle myosin light chain kinase modulates kinase activity and endothelial cytoskeletal dynamics. [PDF]
, 2014 Disruption of the pulmonary endothelial barrier and subsequent vascular leak is a hallmark of acute lung injury. Dynamic rearrangements in the endothelial cell (EC) peripheral membrane and underlying cytoskeleton are critical determinants of barrier ...
C. Naureckas (7923242) +8 more
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Glutathione and Proline Attenuates Injury Induced by Boron Toxicity in Wheat
Journal of Agricultural Sciences, 2023 Given the increasing importance of boron (B) toxicity, the present study investigates the roles of glutathione (20 mM, GSH) and proline (20 mM) in the improvement of wheat (Triticum aestivum cv. Altındane) resistance to B toxicity (10 mM B).
Yavuz Demir, Sakineh M. Kohnehsharhı
doaj +1 more source
Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum [PDF]
, 2007 Proline-specific dipeptidyl peptidase-like (DPP IV; EC 3.4.14.5) activity in bovine serum has attracted little attention despite its ready availability and the paucity of useful proline-cleaving enzymes.
Ruth, Deborah M. +4 more
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Mitochondrial dynamics links PINCH-1 signaling to proline metabolic reprogramming and tumor growth
Cell Stress, 2020 Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants to animals. In bacteria and plants, proline is known to accrue in response to osmotic and other
Ling Guo, Chuanyue Wu
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Formation of bioinorganic complexes by the corrosive adsorption of (S)-proline on Ni/Au(111) [PDF]
, 2015 R.T.S.G. and J.G. acknowledge the Engineering and Physical Sciences Research Council (EPSRC, UK) for the award of a PhD studentship. The research leading to these results has received funding from the European Community’s Seventh Framework Programme (FP7/
Baddeley, Christopher John +10 more
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Proline transport inhibitors trigger differential responses in Trypanosoma cruzi growth inhibition [PDF]
, 2021 Background: Proline is a fundamental amino acid for Trypanosoma cruzi, the etiological agent of Chagas disease. Proline is mainly incorporated from the extracellular medium by amino acid transport systems.
Lucas , Pagura +5 more
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Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline
Memorias do Instituto Oswaldo Cruz, 2009 Trypanosoma cruzi proline racemases (TcPRAC) are homodimeric enzymes that interconvert the L and D-enantiomers of proline. At least two paralogous copies of proline racemase (PR) genes are present per parasite haploid genome and they are differentially ...
Nicolas Coatnoan +3 more
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Frontiers in Molecular Biosciences, 2021 Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain.
Juan Alcantara +7 more
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The study of a new and specific proline cleaving peptidase from bovine serum [PDF]
, 2003 Prolyl oligopeptidase is a serine peptidase characterised by oligoendopeptidase activity. Definitive evidence for the discrete biological role of prolyl oligopeptidase remains unknown, though its role in the maturation and degradation of peptide hormones
Collins, Patrick
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Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae
Microbial Cell, 2019 In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes.
Yukio Mukai +7 more
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