The regulatory mechanisms of proline and hydroxyproline metabolism: Recent advances in perspective
Frontiers in Oncology, 2023 For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily synthesized from glutamine.
James M. Phang
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EFSA Journal, 2012 Following a request from the European Commission, pursuant to Article 13.1 of Regulation (EC) No 1924/2006, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a health claim related to isoleucine‐proline ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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Convenient synthesis of an enantiomerically pure bicyclic proline and its N-oxyl derivatives [PDF]
, 2008 An enantiomerically pure bicyclic proline derivative was prepared by cis-selective allylation and diastereospecific intramolecular alkylation starting from d-pipecolinic acid.
Demizu, Yosuke +4 more
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Proline-Based Boronic Acid Receptors for Chiral Recognition of Glucose [PDF]
, 2018 Chiral recognition remains a major challenge in the area of molecular receptor design. With this research, we set out to explore the use of proline-based receptors for chiral recognition.
Zhang, Miao +17 more
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Disruption of fyn SH3 domain interaction with a proline-rich motif in liver kinase B1 results in activation of AMP-activated protein kinase [PDF]
, 2013 Fyn-deficient mice display increased AMP-activated Protein Kinase (AMPK) activity as a result of Fyn-dependent regulation of Liver Kinase B1 (LKB1) in skeletal muscle.
Bastie, Claire C. +6 more
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Changes in morphology, proline content, and palatability to Helix aspersa, in Plantago lanceolata in response to transplantation and polluted soil [PDF]
, 1992 High concentrations of heavy metals are a cause of stress in plants, many of which respond by accumulating high levels of the amino acid proline. Tolerant and intolerant plants may vary in their response, and this may be reflected in the palatability of ...
Lart, K.M.
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Figure 10. N-Methyl-(2S,4R)-trans-4-Hydroxy-L-Proline
, 2022 Figure 10.
Adryan Fristiohady (12512725)
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Effect of drought stress on yield, proline and chlorophyll contents in three chickpea cultivars [PDF]
, 2010 Drought stress is one of the major abiotic stresses in agriculture worldwide. This study was carried out to investigate the effect of drought stress on proline content, chlorophyll content, photosynthesis and transpiration, stomatal conductance and yield
Siosemardeh, A. +4 more
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