Results 11 to 20 of about 253,684 (257)

Proline Transport and Growth Changes in Proline Transport Mutants of Staphylococcus aureus

open access: yesMicroorganisms, 2022
Staphylococcus aureus is a major cause of skin/soft tissue infections and more serious infections in humans. The species usually requires the importation of proline to be able to survive. Previous work has shown that single mutations in genes that encode
William R. Schwan
doaj   +1 more source

Proline transporters ProT and PutP are required for Staphylococcus aureus infection.

open access: yesPLoS Pathogens, 2023
Proline acquired via specific transporters can serve as a proteinogenic substrate, carbon and nitrogen source, or osmolyte. Previous reports have documented that Staphylococcus aureus, a major community and nosocomial pathogen, encodes at least four ...
McKenzie K Lehman   +5 more
doaj   +1 more source

Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities

open access: yesBiology, 2023
Proline isomerization, the process of interconversion between the cis- and trans-forms of proline, is an important and unique post-translational modification that can affect protein folding and conformations, and ultimately regulate protein functions and
Deepti Gurung   +5 more
doaj   +1 more source

Glutathione and Proline Attenuates Injury Induced by Boron Toxicity in Wheat

open access: yesJournal of Agricultural Sciences, 2023
Given the increasing importance of boron (B) toxicity, the present study investigates the roles of glutathione (20 mM, GSH) and proline (20 mM) in the improvement of wheat (Triticum aestivum cv. Altındane) resistance to B toxicity (10 mM B).
Yavuz Demir, Sakineh M. Kohnehsharhı
doaj   +1 more source

Effect of Humic Acid and Vermicompost on Some Vegetative Indices and Proline Content of Catharanthus roseous under Low Water Stress [PDF]

open access: yesمحیط زیست و مهندسی آب, 2023
To investigate the effect of vermicompost (0, 25, and 50%) and humic acid (0, 50, and 100 mg/l) on some traits of Catharanthus roseous under low water stress (50 and 100% field capacity), a factorial experiment based on a completely randomized design was
Saleh AlhverdiZadeh, Elham Danaee
doaj   +1 more source

Arabidopsis AMINO ACID PERMEASE1 Contributes to Salt Stress-Induced Proline Uptake from Exogenous Sources

open access: yesFrontiers in Plant Science, 2017
Stress-induced proline accumulation in plants is thought to result primarily from enhanced proline biosynthesis and decreased proline degradation. To identify regulatory components involved in proline transport, we screened for Arabidopsis thaliana T-DNA
Ting Wang   +10 more
doaj   +1 more source

Proline to the rescue [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Protein misfolding is now recognized to be a major contributing factor in a number of protein folding diseases, including amyotropic laterial sclerosis, cystic fibrosis, Alzheimer's disease, Parkinson's disease, and a host of many different amyloidosis diseases.
openaire   +2 more sources

Mitochondrial dynamics links PINCH-1 signaling to proline metabolic reprogramming and tumor growth

open access: yesCell Stress, 2020
Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants to animals. In bacteria and plants, proline is known to accrue in response to osmotic and other
Ling Guo, Chuanyue Wu
doaj   +1 more source

An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

open access: yesFrontiers in Molecular Biosciences, 2021
Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain.
Juan Alcantara   +7 more
doaj   +1 more source

Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline

open access: yesMemorias do Instituto Oswaldo Cruz, 2009
Trypanosoma cruzi proline racemases (TcPRAC) are homodimeric enzymes that interconvert the L and D-enantiomers of proline. At least two paralogous copies of proline racemase (PR) genes are present per parasite haploid genome and they are differentially ...
Nicolas Coatnoan   +3 more
doaj   +1 more source

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