Results 11 to 20 of about 303,245 (307)

The correlation between proline/P5C cycle and the response to avirulent pathogen infection in Arabidopsis

open access: yesCurrent Plant Biology, 2023
Proline/P5C cycle between mitochondria and cytosol, play important roles in energy supply and ROS (Reactive oxygen species) generation in mammalian cell.
Wenhan Ying   +6 more
doaj   +1 more source

The sodium/proline transporter PutP of Helicobacter pylori. [PDF]

open access: yesPLoS ONE, 2013
Helicobacter pylori is cause of chronic gastritis, duodenal ulcer and gastric carcinoma in humans. L-proline is a preferred energy source of the microaerophilic bacterium. Previous analyses revealed that HpputP and HpputA, the genes that are predicted to
Araceli Rivera-Ordaz   +8 more
doaj   +1 more source

Proline Transport and Growth Changes in Proline Transport Mutants of Staphylococcus aureus

open access: yesMicroorganisms, 2022
Staphylococcus aureus is a major cause of skin/soft tissue infections and more serious infections in humans. The species usually requires the importation of proline to be able to survive. Previous work has shown that single mutations in genes that encode
William R. Schwan
doaj   +1 more source

Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome. [PDF]

open access: yesPLoS ONE, 2013
Proline is an anomalous amino acid. Its nitrogen atom is covalently locked within a ring, thus it is the only proteinogenic amino acid with a constrained phi angle.
Alexander A Morgan, Edward Rubenstein
doaj   +1 more source

Enzymatic production of trans‐4‐hydroxy‐l‐proline by proline 4‐hydroxylase

open access: yesMicrobial Biotechnology, 2021
Summary Trans‐4‐hydroxy‐l‐proline (Hyp) is a useful chiral building block for production of many nutritional supplements and pharmaceuticals. However, it is still challenging for industrial production of Hyp due to heavy environmental pollution and low ...
Xiulai Chen   +4 more
doaj   +1 more source

Proline transporters ProT and PutP are required for Staphylococcus aureus infection.

open access: yesPLoS Pathogens, 2023
Proline acquired via specific transporters can serve as a proteinogenic substrate, carbon and nitrogen source, or osmolyte. Previous reports have documented that Staphylococcus aureus, a major community and nosocomial pathogen, encodes at least four ...
McKenzie K Lehman   +5 more
doaj   +1 more source

Mechanically Enhanced Proline Ring-Opening in Proteins [PDF]

open access: yes, 2022
Proteins such as collagen and elastin are subjected to highly repetitive stresses in the cardiovascular system. These proteins can have half-lives of many decades and, therefore, experience many tens or hundreds of millions of stress-strain cycles.
Jan, Hoh
core   +1 more source

Arabidopsis AMINO ACID PERMEASE1 Contributes to Salt Stress-Induced Proline Uptake from Exogenous Sources

open access: yesFrontiers in Plant Science, 2017
Stress-induced proline accumulation in plants is thought to result primarily from enhanced proline biosynthesis and decreased proline degradation. To identify regulatory components involved in proline transport, we screened for Arabidopsis thaliana T-DNA
Ting Wang   +10 more
doaj   +1 more source

Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities

open access: yesBiology, 2023
Proline isomerization, the process of interconversion between the cis- and trans-forms of proline, is an important and unique post-translational modification that can affect protein folding and conformations, and ultimately regulate protein functions and
Deepti Gurung   +5 more
doaj   +1 more source

Proline to the rescue [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Protein misfolding is now recognized to be a major contributing factor in a number of protein folding diseases, including amyotropic laterial sclerosis, cystic fibrosis, Alzheimer's disease, Parkinson's disease, and a host of many different amyloidosis diseases.
openaire   +2 more sources

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