Results 41 to 50 of about 312,564 (296)

Serum progesterone concentration on pregnancy test day might predict ongoing pregnancy after controlled ovarian stimulation and fresh embryo transfer

Frontiers in Endocrinology, 2023
Progesterone (P4) is essential for pregnancy. A controlled ovarian stimulation (COS) leads to a iatrogenic luteal defect that indicates a luteal phase support (LPS) at least until pregnancy test day. Some clinicians continue the LPS until week 8 or later,
Marie Duport Percier, Sophie Brouillet, Sophie Brouillet, Caroline Mollevi, Martha Duraes, Tal Anahory, Noemie Ranisavljevic   +6 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Antidepressants in pregnancy and breastfeeding [PDF]

, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ASSESSMENT OF THE PREDISPOSING FACTORS OF PROLONGED PREGNANCY

نشریه پرستاری ایران, 2004
Lengthened pregnancy after the 41st week will create problems for mother, fetus and newborn. Assessment of the predisposing factors of prolonged pregnancy is a research priority.
F Oskouie, KH. Ramezani, S. Taavoni, H. Haghani   +3 more
doaj  

Retrospective Analysis of Maternal and Perinatal Outcomes in Late Term Pregnancies

Bagcilar Medical Bulletin
Objective: The purpose of this study was to evaluate the maternal and perinatal outcomes of pregnancies beyond 40 weeks gestation. Method: The study included 476 patients who gave birth between October 2016 and October 2017 at the Obstetrics and ...
Damla Yasemin Yenliç Kay, Yücel Kaya, Veli Mihmanlı, Murat İbrahim Toplu, Yağmur Ölmez   +4 more
doaj   +1 more source

Effectiveness of multiple versus once-only membrane sweeping at term in preventing prolonged pregnancy: A randomised controlled trial

Scientific African, 2023
Background: Between 4 and 18% of pregnancies are prolonged. Prolonged pregnancy is associated with adverse maternal and perinatal outcomes. Objectives: To compare the effectiveness of once-only versus multiple (weekly) membrane sweeping in reducing the ...
Chidiebere Njoku, James Enimi Omietimi, Peter Chibuzor Oriji, Egbaname Obozegie Samuel Aigere, Stephen Adeniyi Afolabi, Ebiye Serena Tekenah, Akaninyene Eseme Ubom, Panebi Yao Bosrotsi, Oforbuike Samuel Odo   +8 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source