Results 51 to 60 of about 312,564 (296)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Aspectos clínico-epidemiológicos de la inducción del parto en el embarazo postérmino Clinical and epidemiological features of inducing labor in post-term pregnancy

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2010
El embarazo postérmino es una entidad obstétrica muy discutida en la literatura médica debido a los diferentes criterios empleados con relación al diagnóstico, control prenatal, conducta a tomar y manejo intraparto.
Migdalia de las Mercedes Peña Abraham   +4 more
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

\ud Case Report: Unsuspected Uterine Choriocarcinoma with Lung Metastasis\ud [PDF]

open access: yes, 2010
Choriocarcinoma is a rare form of cancer which commonly occurs in women of reproductive age, rarely in post-menopausal women and in women under 20 years of age.
Faustine, Lucas   +8 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Zinc in pregnancy, associated with prolonged labor

open access: yesCaspian Journal of Reproductive Medicine, 2015
Introduction: It is plausible that pregnancy may result in a decrease in the serum zinc concentration. The concentration of serum zinc is an important determinant of maternal complications.
Sare Bakouei   +3 more
doaj   +2 more sources

Mild Clinical Presentation of Acute Fatty Liver in the Second Trimester of Pregnancy

open access: yesCase Reports in Obstetrics and Gynecology, 2011
We report a case of 29 years old woman who was diagnosed with acute fatty liver of pregnancy at 23 weeks of gestation with unusual evolution (pregnancy prolonged until 36 weeks of gestation) to draw attention on the possibility of occurrence of this ...
Alaeddine Yassin   +6 more
doaj   +1 more source

Hubungan Anemia pada Kehamilan Dengan Inpartu Kala II Lama di BPM Ny. Suhariyati Surabaya

open access: yesJurnal Ilmiah Kesehatan, 2016
Relations of Anemia in Pregnancy With Inpartu Kala II Lama in BPM Ny. Suhariyati Surabaya. Anemia in pregnancy in Indonesia is still high, with a national rate of 65% which each region has different variations, anemia is one of the causes of prolonged ...
Ratna Ariesta, Dwi Andriani
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

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