Early Identification of Prolonged QT Interval for Prevention of Sudden Infant Death. [PDF]
Front Pediatr, 2021 Sarquella-Brugada G +24 more
europepmc +1 more source
Survey concerning internal medicine physicians and prolonged QT interval: Knowledge and treatment practices. [PDF]
World J Cardiol, 2021 Wendl E, Telles N, Wall GC.
europepmc +1 more source
Facilitation of I Kr current by some hERG channel blockers suppresses early afterdepolarizations. [PDF]
, 2019 Drug-induced block of the cardiac rapid delayed rectifying potassium current (I Kr), carried by the human ether-a-go-go-related gene (hERG) channel, is the most common cause of acquired long QT syndrome.
Chen, I-Shan +6 more
core +1 more source
Correlation between seizure in children and prolonged QT interval
ARYA Atherosclerosis, 2013 BACKGROUND: Long QT is a cardiac electrical disorder. One of the symptoms of long QT caused by fatal ventricular arrhythmia is seizure. In some studies it was indicated that up to 35% of seizures induced by long QT may be misdiagnosed as other causes of ...
Saeid Sadrnia +2 more
doaj
Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]
, 2001 Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core
Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K [PDF]
, 2018 SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric Gi proteins in many cell types, including cardiomyocytes.
Al-Owais, Moza +6 more
core +1 more source
The QT interval in lightning injury with implications for the cessation of metabolism hypothesis [PDF]
An hypothesis is presented to provide an alternative to the Cessation of Metabolism hypothesis often invoked in lightning injury. Cessation of Metabolism has been proposed to explain the observation of good recovery after a prolonged period in cardiac ...
Andrews, Christopher J. +2 more
core +1 more source
A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs). [PDF]
, 1998 MinK and MinK-related peptide I (MiRPI) are integral membrane peptides with a single transmembrane span. These peptides are active only when co-assembled with pore-forming K+ channel subunits and yet their role in normal ion channel behaviour is ...
Abbott, GW, Goldstein, SA
core
, 2017 Blockage of some ion channels and in particular, the hERG cardiac potassium channel delays cardiac repolarization and can induce arrhythmia. In some cases it leads to a potentially life-threatening arrhythmia known as Torsade de Pointes (TdP).
Buzatu, Dan +3 more
core +1 more source
Clinical-pharmacological aspects of the safe use of medicines, causing prolongation of QT interval
Безопасность и риск фармакотерапии, 2018 Specific aspects of manifestation of prolonged QT syndrome, developed during the use of drugs belonging to different pharmacological groups are discussed. It analyses data on dangerous combinations of drugs that prolong the QT interval.
O. A. Demidova +3 more
doaj