Results 101 to 110 of about 113,542 (365)

Methods of Assessment and Clinical Relevance of QT Dynamics [PDF]

open access: yes, 2005
The dependence on heart rate of the QT interval has been investigated for many years and several mathematical formulae have been proposed to describe the QT interval/heart rate (or QT interval/RR interval) relationship. While the most popular is Bazett’s
Agata, Musialik-Lydka   +4 more
core  

Drug-mediated shortening of action potentials in LQTS2 hiPSC-cardiomyocytes [PDF]

open access: yes, 2017
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart.
Denning, Chris   +6 more
core   +3 more sources

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia   +11 more
wiley   +1 more source

Methadone and Corrected QT Prolongation in Pain and Palliative Care Patients: A Case–Control Study [PDF]

open access: yes, 2017
Background: Methadone (ME) is commonly used in pain and palliative care (PPC) patients with refractory pain or intolerable opioid adverse effects (AEs).
Brown, Jack   +3 more
core   +2 more sources

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout   +6 more
wiley   +1 more source

Long QT interval in resting electrocardiogram – and what next? Sports cardiologist’s pointofview. Part 1. From electrophysiology to diagnostics

open access: yesPediatria i Medycyna Rodzinna, 2014
Electrocardiography is the most common and available cardiovascular diagnostic procedure and an important tool in everyday clinical practice of a family physician. Electrocardiogram interpretation is therefore an invaluable clinical skill.
Zbigniew Krenc
doaj   +1 more source

Rivastigmine and QT interval prolongation [PDF]

open access: yesBritish Journal of Psychiatry, 2003
Walsh & Dourish ( [2002][1]) reported that a 78-year-old man, receiving a number of medications and with a history of myocardial infarction and hypokalaemia, developed an abnormal QTc interval a week after starting rivastigmine treatment.
openaire   +1 more source

Cardiorespiratory cross‐frequency coupling biomarker for sudden unexpected death in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) often follows generalized tonic–clonic seizures during sleep, likely resulting from impaired brainstem cardiorespiratory function. We used ictal electrocardiogram (ECG)‐based cross‐frequency phase–amplitude coupling (PAC) to detect cardiorespiratory disruptions, comparing SUDEP to non‐SUDEP
Adam C. Gravitis   +7 more
wiley   +1 more source

A case of hypoglycemiainduced QT prolongation leading to torsade de pointes and a review of pathophysiological mechanisms

open access: yesClinics and Practice, 2017
Torsades de pointes is a life-threatening cardiac arrhythmia. Occurrence of this arrhythmia as a result of hypoglycemia has not been reported in the literature.
Faris Hannoodi   +5 more
doaj   +1 more source

Multifactorial QT interval prolongation.

open access: yesCardiology journal, 2010
Acquired long QT interval has been widely reported to be a consequence of drug therapy and electrolyte disturbances. We describe two cases of multifactorial acquired QT interval prolongation and torsades de pointes. In the first case, the drugs venlafaxine, amiodarone and domperidone may have contributed to QT interval prolongation in a patient with ...
Geneviève, Digby   +6 more
openaire   +1 more source

Home - About - Disclaimer - Privacy