Results 101 to 110 of about 688,963 (289)
Propagating Waves Transverse to the Magnetic Field in a Solar Prominence
, 2013 We report an unusual set of observations of waves in a large prominence pillar which consist of pulses propagating perpendicular to the prominence magnetic field.
Knizhnik, K. +5 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Quale nozione di pluralismo nell’EMFA?
Rivista Italiana di Informatica e DirittoL’articolo si propone, attraverso l’analisi del regolamento (UE) 2024/1083, da un lato di verificare quale nozione di pluralismo abbia tenuto presente il legislatore europeo nell’EMFA (European Media Freedom Act) e, dall’altro lato, di individuare le ...
Ottavio Grandinetti
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Nonlinear MHD waves in a Prominence Foot
, 2015 We study nonlinear waves in a prominence foot using 2.5D MHD model motivated by recent high-resolution observations with Hinode/SOT in Ca~II emission of a prominence on October 10, 2012 showing highly dynamic small-scale motions in the prominence ...
Knizhnik, Kalman +3 more
core +2 more sources
Proceedings of the International Astronomical Union, 2013 AbstractQuiescent solar prominences are cool and dense plasma clouds located inside the hot and less dense solar corona. They are highly dynamic structures displaying flows, instabilities, oscillatory motions, etc. The oscillations have been mostly interpreted in terms of magnetohydrodynamic (MHD) waves, which has allowed to perform prominence ...
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Phonetic Detail in German Syllable Pronunciation: Influences of Prosody and Grammar
Frontiers in Psychology, 2014 This study presents two experiments designed to disentangle various influences on syllable pronunciation. Target syllables were embedded in carrier sentences, read aloud by native German participants, and analyzed in terms of syllable and vowel duration,
Barbara eSamlowski +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source