Results 131 to 140 of about 201,462 (304)
Foundations of a Theory of Prominence in the Decimal System - Part I: Numerical Response as a Process, Exactness, Scales, and Structure of Scales [PDF]
Starting point of the theory of prominence is the observation that the selection of a numerical response is performed by a process of stepwise refinement of a reasonable answer until the available information does not permit a further specification.
Wulf Albers
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Open LinguisticsThere has been growing debate about the special status of object marking in sign languages. In this article, we contribute evidence for the existence of a differential object marker in DGS (German Sign Language). Based on data from the Public DGS Corpus,
de Souza Santos Thiago +2 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Cognitive and probabilistic basis of prominence perception in speech
, 2017 The research in this thesis examines the topic of the cognitive and probabilistic nature of prominence perception in speech. In recent years, there has been an accumulating number of studies from linguistics, phonetics, and neuroscience providing ...
Kakouros, Sofoklis
core +1 more source
Quale nozione di pluralismo nell’EMFA?
Rivista Italiana di Informatica e DirittoL’articolo si propone, attraverso l’analisi del regolamento (UE) 2024/1083, da un lato di verificare quale nozione di pluralismo abbia tenuto presente il legislatore europeo nell’EMFA (European Media Freedom Act) e, dall’altro lato, di individuare le ...
Ottavio Grandinetti
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source