Results 61 to 70 of about 688,963 (289)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
SDO/AIA Detection of Solar Prominence Formation within a Coronal Cavity
, 2012 We report the first analyses of SDO/AIA observations of the formation of a quiescent polar crown prominence in a coronal cavity. The He II 304 \AA\ (log T_{max} ~ 4.8 K) data show both the gradual disappearance of the prominence due to vertical drainage ...
Antiochos +30 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Games, 2017 Using a unique experimental data set, we investigate how asymmetric legal rights shape bargainers’ aspiration levels through moral entitlements derived from equity norms and number prominence.
Heike Hennig-Schmidt, Gari Walkowitz
doaj +1 more source
Standing out in context: Prominence in the production and perception of public speech
Laboratory Phonology, 2023 This study investigates the relationship between signal-based factors and discourse context in the production and perception of prominence, extending prior work on prominence in American English by examining speech from complete TED Talks as examples of ...
Jennifer Cole, Stefan Baumann, Suyeon Im
doaj +2 more sources
Structure of prominence legs: Plasma and magnetic field [PDF]
, 2015 We investigate the properties of a `solar tornado' observed on 15 July 2014, and aim to link the behaviour of the plasma to the internal magnetic field structure of the associated prominence.
Ariste, A. López +3 more
core +4 more sources
3D WHOLE-PROMINENCE FINE STRUCTURE MODELING. II. PROMINENCE EVOLUTION [PDF]
The Astrophysical Journal, 2015 We use the new three-dimensional (3D) whole-prominence fine structure model to study the evolution of prominences and their fine structures in response to changes in the underlying photospheric magnetic flux distribution. The applied model combines a detailed 3D prominence magnetic field configuration with a realistic description of the prominence ...
Stanislav Gunár, Duncan H. Mackay
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Siriraj Medical Journal, 2006 The human face develops between the fourth and eighth week after conception. Its development can be traced to five facial primordia appearing around the stomodeum in the fourth week.
Jantima Roongruangchai +2 more
doaj