Results 51 to 60 of about 145,461 (218)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Prosodic focus in English vs. French: A scope account
Glossa, 2018 We compare the use of prosodic prominence in English and French to convey focus. While previous studies have found these languages, and Germanic vs. Romance more generally, to differ in their use of prominence to encode focus (e.g., Ladd 1990; 1996; 2008;
Heather Goad +2 more
doaj +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The interplay of prominence-lending factors and language production in children
Frontiers in Language SciencesSeveral factors influence how adult speakers produce an utterance and which element they choose to start with. For example, German-speaking adults are more likely to begin an utterance with an element if it is (a) in their focus of attention, (b) animate
Sarah Dolscheid, Martina Penke
doaj +1 more source
An experimental investigation of the binding options of demonstrative pronouns in German
Glossa, 2018 This paper discusses data from two self-paced reading experiments as well as an acceptability rating study that shed light on the binding behaviour of demonstrative pronouns as opposed to personal pronouns.
Andreas Brocher, Stefan Hinterwimmer
doaj +2 more sources
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Acoustic classification of focus: On the web and in the lab
Laboratory Phonology, 2017 We present a new methodological approach which combines both naturally-occurring speech harvested on the web and speech data elicited in the laboratory.
Jonathan Howell +2 more
doaj +2 more sources
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Differential object marking in sign languages
Glossa, 2019 Sign languages are sometimes claimed to lack argument marking, yet they exhibit many devices to track and disambiguate referents. In this paper, I will argue that there are devices found across sign languages that demonstrate how object marking is a ...
Carl Börstell
doaj +2 more sources