Results 141 to 150 of about 22,877 (292)

Modeling multiphase plasma in the corona: prominences and rain

open access: yesLiving Reviews in Solar Physics
We review major achievements in our understanding of multiphase coronal plasma, where cool-dense and hot-tenuous matter coexists, brought about by advances in modeling and theory, inspired by observations.
Rony Keppens, Yuhao Zhou, Chun Xia
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Development of Torus and Kink Instabilities in Eruptive Prominences

open access: yesThe Astrophysical Journal
Several filament eruptions with pronounced writhing of the axis of the structure are analyzed. Initially, smooth arches of eruptive filaments are transformed into large-scale helical structures with at least one complete turn due to the development of ...
Boris Filippov
doaj   +1 more source

Spectral Diagnostics of Active Prominences

open access: yes, 2007
Active prominences exhibit plasma motions, resulting in difficulties with the interpretation of spectroscopic observations. These solar features being strongly influenced by the radiation coming from the solar disk, Doppler dimming or brightening effects
Gouttebroze, Pierre   +2 more
core  

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

The Bright Rim Prominences according to 2.5D Radiative Transfer

open access: yesThe Astrophysical Journal Letters
Solar prominences observed close to the limb commonly include a bright feature that, from the perspective of the observer, runs along the interface between itself and the underlying chromosphere. Despite several idealized models being proposed to explain
Jack M. Jenkins   +4 more
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen   +10 more
wiley   +1 more source

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