Results 131 to 140 of about 2,113,360 (356)
FEBS Letters, EarlyView.We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon +5 more
wiley +1 more source
American Journal of Human Genetics, 2006 A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease as well as brain morphometry and function. Here, we show that HTTLPR is functionally triallelic.
Xian-zhang Hu +11 more
semanticscholar +1 more source
Uncovering Political Promotion in China: A Network Analysis of Patronage Relationship in Autocracy [PDF]
arXiv, 2019 Understanding patronage networks in Chinese Bureaucracy helps us quantify the promotion mechanism underlying autocratic political systems. Although there are qualitative studies analyzing political promotions, few use quantitative methods to model promotions and make inferences on the fitted mathematical model.
arxiv
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Carbon TrendsIn response to the escalating demand for cleaner energy sources, this study investigates the potential of carefully selected functionalized graphene-based materials for enhancing hydrogen sulphide (H2S) removal in fuel streams, utilizing semi-empirical ...
Toyese Oyegoke +3 more
doaj
Gabriel Lafond and Ambrose W. Thompson: Neglected Isthmian Promoters [PDF]
, 1956 Paul J. Scheips
openalex +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Careful About What App Promotion Ads Recommend! Detecting and Explaining Malware Promotion via App Promotion Graph [PDF]
arXivIn Android apps, their developers frequently place app promotion ads, namely advertisements to promote other apps. Unfortunately, the inadequate vetting of ad content allows malicious developers to exploit app promotion ads as a new distribution channel for malware.
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source