Results 201 to 210 of about 556,506 (299)

Evolutionary Process Underlying Receptor Gene Expansion and Cellular Divergence of Olfactory Sensory Neurons in Honeybees. [PDF]

Mol Biol Evol
Zhang W, Nie Y, Xu T, Li Y, Xu Y, Chen X, Shi P, Liu F, Zhao H, Ma Q, Xu J.   +10 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Acute myeloid leukemia-derived extracellular vesicles induced DNA methylation changes responsible for inflammatory program in normal hematopoietic stem progenitor cells. [PDF]

Front Immunol
Lamorte D, Calice G, Trino S, Santodirocco M, Caivano A, De Luca L, Laurenzana I.   +6 more
europepmc   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Peripheral tissue BDNF expression is affected by promoter IV defect and enriched environments in mice: negative hippocampus-intestine and positive thymus-serum-muscle correlations. [PDF]

Mol Med
Wang J, Schupp W, Sakata K.
europepmc   +1 more source

Regulation of WNT16 in bone may involve upstream enhancers within CPED1. [PDF]

Sci Rep
Martínez-Gil N, Herrera-Ubeda C, Gritti N, Roca-Ayats N, Ugartondo N, Garcia-Giralt N, Ovejero D, Nogués X, Garcia-Fernàndez J, Grinberg D, Balcells S.   +10 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Transcriptional regulation of two redundant 3-bromo-4-hydroxybenzoate catabolic operons via two different regulatory modes in <i>Pigmentiphaga kullae</i> strain H8. [PDF]

Appl Environ Microbiol
Ke Z, Yang K, Zhang Z, Guo R, Gao Y, Lan M, Jiang J, Chen K.   +7 more
europepmc   +1 more source

Case of <i>bla_KPC-12</i> -carrying hypervirulent <i>Klebsiella pneumoniae</i> from bloodstream infection in China. [PDF]

JAC Antimicrob Resist
Chen A, Wang H, Zhang J, Sun Y, Chen G, Zhou H.   +5 more
europepmc   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source