Results 221 to 230 of about 556,506 (299)

Flipons enable genomes to learn by intermediating the exchange of energy for information. [PDF]

J R Soc Interface
Herbert A.
europepmc   +1 more source

Effects of Dalcroze Eurhythmics Exercise Versus Multicomponent Exercise on Physical and Cognitive Function, and Falls in Older Adults: The EPHYCOS Randomized Controlled Trial

Advanced Biology, EarlyView.
In this randomized clinical trial conducted among 142 community‐dwelling older adults at high risk for falls over 12 months, a Dalcroze Eurhythmics exercise intervention (once weekly, group‐based) improved a variety of physical and cognitive/executive function outcomes compared with a multicomponent exercise intervention (twice weekly, group‐ and home ...
Mélany Hars, Natalia Fernandez, François Herrmann, René Rizzoli, Serge Ferrari, Christophe Graf, Patrik Vuilleumier, Andrea Trombetti   +7 more
wiley   +1 more source

Long-read sequencing reveals novel structural variation markers for key agronomic and quality traits of food-grade soybean. [PDF]

Front Plant Sci
Wang Z, Belay K, Paterson J, Bewick P, Singer W, Song Q, Zhang B, Li S.   +7 more
europepmc   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Predicting gene expression from histone marks using chromatin deep learning models depends on histone mark function, regulatory distance and cellular states. [PDF]

Nucleic Acids Res
Murphy AE, Askarova A, Lenhard B, Skene NG, Marzi SJ.   +4 more
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing. [PDF]

J Biol Eng
Yanagi T, Phen SF, Ayala J, Aydin DE, Jaramillo S, Truong DM.   +5 more
europepmc   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Comprehensive mapping of genetic variation at Epromoters reveals pleiotropic association with multiple disease traits. [PDF]

Nucleic Acids Res
Wan J, van Ouwerkerk A, Mouren JC, Heredia C, Pradel L, Ballester B, Andrau JC, Spicuglia S.   +7 more
europepmc   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source