Results 271 to 280 of about 795,608 (343)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

A pilot multi-omics study reveals genetic mechanisms regulating milk component traits in dairy cattle. [PDF]

Commun Biol
Zheng W, Zhang J, Huang J, Han B, Liu Y, Sun D.   +5 more
europepmc   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Systematic approach for dissecting promoters and designing transform systems in microalgae. [PDF]

Microb Cell Fact
Gan Q, Yu X, Jiang X, Huang X, Xin Y, Lu Y.   +5 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

DNA Methylation and Transcript Variant Analysis of <i>CDKN2A</i> Exon 2 Despite High Sequence Identity with <i>CDKN2B</i> Exon 2. [PDF]

Int J Mol Sci
Zappe K, Jenik A, Berger D, Uhlik L, Heffeter P, Cichna-Markl M.   +5 more
europepmc   +1 more source

Evaluation of the Global White Lupin Collection Reveals Significant Associations Between Homologous <i>FLOWERING LOCUS T</i> Indels and Flowering Time, Providing Validated Markers for Tracking Spring Ecotypes Within a Large Gene Pool. [PDF]

Int J Mol Sci
Bielski W, Surma A, Książkiewicz M, Rychel-Bielska S.   +3 more
europepmc   +1 more source

Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease. [PDF]

Genome Med
Martin-Geary AC, Blakes AJM, Dawes R, Findlay SD, Lord J, Dong S, Walker S, Talbot-Martin J, Wieder N, D'Souza EN, Fernandes M, Hilton S, Lahiri N, Campbell C, Jenkinson S, DeGoede CGEL, Anderson ER, Candler T, Firth H, Burge CB, Sanders SJ, Ellingford J, Baralle D, Banka S, Whiffin N.   +24 more
europepmc   +1 more source

Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure. [PDF]

Clin Epigenetics
Guo Z, Liu Y, Zhou Z, Chen J, Guo L, Liang K, Hao Y, Hao B, Yang B, Liao S.   +9 more
europepmc   +1 more source