Results 281 to 290 of about 390,492 (308)
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Environmental Toxicology and Pharmacology, 2014
The purpose of this study was to determine the interethnic differences of four CYP1A2 drug metabolizing enzyme variants. A total of 404 Roma and 396 Hungarian healthy subjects were genotyped for -163C>A, -729C>T, -2467delT and -3860G>A variants of CYP1A2 by RT-PCR and PCR-RFLP technique.
Renata, Szalai +7 more
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The purpose of this study was to determine the interethnic differences of four CYP1A2 drug metabolizing enzyme variants. A total of 404 Roma and 396 Hungarian healthy subjects were genotyped for -163C>A, -729C>T, -2467delT and -3860G>A variants of CYP1A2 by RT-PCR and PCR-RFLP technique.
Renata, Szalai +7 more
openaire +2 more sources
BLOOD COAGULATION & FIBRINOLYSIS, 1998
Evidence suggests that an allelic variation in the beta fibrinogen gene may confer an increased risk of coronary artery disease and stroke. The role of the beta fibrinogen gene polymorphism and fibrinogen levels in ischemic stroke has not been determined in Japanese, who are more prone to stroke than to coronary artery disease compared with Caucasians.
S, Nishiuma +8 more
openaire +2 more sources
Evidence suggests that an allelic variation in the beta fibrinogen gene may confer an increased risk of coronary artery disease and stroke. The role of the beta fibrinogen gene polymorphism and fibrinogen levels in ischemic stroke has not been determined in Japanese, who are more prone to stroke than to coronary artery disease compared with Caucasians.
S, Nishiuma +8 more
openaire +2 more sources
Arthritis & Rheumatism, 2001
To determine whether the haplotypes formed on the basis of single-base-exchange polymorphisms at positions -1082, -819, or -592 of the interleukin-10 (IL-10) gene predispose subjects to primary Sjögren's syndrome (SS).The frequency of IL-10 polymorphisms was analyzed in 62 patients with primary SS and in 400 healthy subjects.
J, Hulkkonen +5 more
openaire +2 more sources
To determine whether the haplotypes formed on the basis of single-base-exchange polymorphisms at positions -1082, -819, or -592 of the interleukin-10 (IL-10) gene predispose subjects to primary Sjögren's syndrome (SS).The frequency of IL-10 polymorphisms was analyzed in 62 patients with primary SS and in 400 healthy subjects.
J, Hulkkonen +5 more
openaire +2 more sources
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2013
The purpose of this study was to discuss the relationship between genetic polymorphism of promoter region let-7 and genetic susceptibility to hepatocellular carcinoma (HCC) in Chinese population.In this case-control study, 1300 cases of HBV positive patients were recruited in case group and another 1344 cases of persistent chronic HBV carriers were ...
Fang, Huang +4 more
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The purpose of this study was to discuss the relationship between genetic polymorphism of promoter region let-7 and genetic susceptibility to hepatocellular carcinoma (HCC) in Chinese population.In this case-control study, 1300 cases of HBV positive patients were recruited in case group and another 1344 cases of persistent chronic HBV carriers were ...
Fang, Huang +4 more
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Genetic variants in the promoter region of the ALOX5AP gene and susceptibility of ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland), 2012Despite accumulating evidence supporting the association between variants of the ALOX5AP gene and atherosclerotic vascular events, the precise mechanism is still unclear. No variants in the coding sequence that lead to amino acid substitution have been found.
Ruijun, Ji +5 more
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Genetic polymorphism in the IL-10 promoter region in renal transplantation
Transplantation Proceedings, 1999T, Kobayashi +10 more
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Characterization of genetic variants in the NFKBIA promoter region in multiple sclerosis
Journal of Neuroimmunology, 2014Yan, Jun +4 more
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Anales espanoles de pediatria, 2002
A relationship between polymorphism in the promoter region of the UGT1A1 gene (associated with Gilbert's syndrome) and the development of jaundice has recently been demonstrated. This polymorphism is due to (TA)7 instead of wild-type (TA)6.To investigate the relationship between Gilbert's syndrome and neonatal jaundice by evaluating the distribution of
M L, Seco +6 more
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A relationship between polymorphism in the promoter region of the UGT1A1 gene (associated with Gilbert's syndrome) and the development of jaundice has recently been demonstrated. This polymorphism is due to (TA)7 instead of wild-type (TA)6.To investigate the relationship between Gilbert's syndrome and neonatal jaundice by evaluating the distribution of
M L, Seco +6 more
openaire +1 more source
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2006
To examine the genetic polymorphisms in the promoter region of cyclooxygenase-2 ( COX-2) and evaluate their association with the risk of gastric cancer.Single-strand conformational polymorphism and DNA sequencing were used to screen the genetic variants of the COX-2 promoter region.
Xue-mei, Zhang +6 more
openaire +1 more source
To examine the genetic polymorphisms in the promoter region of cyclooxygenase-2 ( COX-2) and evaluate their association with the risk of gastric cancer.Single-strand conformational polymorphism and DNA sequencing were used to screen the genetic variants of the COX-2 promoter region.
Xue-mei, Zhang +6 more
openaire +1 more source