Results 1 to 10 of about 293,755 (268)
Transcriptional control by enhancers and enhancer RNAs [PDF]
Transcription, 2019 The regulation of gene expression is a fundamental cellular process and its misregulation is a key component of disease. Enhancers are one of the most salient regulatory elements in the genome and help orchestrate proper spatiotemporal gene expression during development, in homeostasis, and in response to signaling.
Michael W. Lewis +2 more
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Journal of Bioethical Inquiry, 2022 AbstractTransgender healthcare faces a dilemma. On the one hand, access to certain medical interventions, including hormone treatments or surgeries, where desired, may be beneficial or even vital for some gender dysphoric trans people. But on the other hand, access to medical interventions typically requires a diagnosis, which, in turn, seems to imply ...
Hazem Zohny +2 more
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Molecular Therapy: Nucleic Acids, 2021 Glioma is the most common malignancy in the central nervous system with no immediate prospect of a cure. Comprehensive understanding on the pathogenesis of the disorder contributes to a better outcome.
Meixiong Cheng +5 more
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Enhancing Photorealism Enhancement
IEEE Transactions on Pattern Analysis and Machine Intelligence, 2023 Code and data available at https://github.com/intel-isl/PhotorealismEnhancement Video available at https://youtu.be ...
Stephan R. Richter +2 more
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Autonomy and Enhancement [PDF]
Neuroethics, 2013 Some have objected to human enhancement on the grounds that it violates the autonomy of the enhanced. These objections, however, overlook the interesting possibility that autonomy itself could be enhanced. How, exactly, to enhance autonomy is a difficult problem due to the numerous and diverse accounts of autonomy in the literature.
Schaefer G.O., Kahane G., Savulescu J.
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Achievement and Enhancement [PDF]
Canadian Journal of Philosophy, 2019 AbstractWe engage with the nature and the value of achievement through a critical examination of an argument according to which biomedical “enhancement” of our capacities is impermissible because enhancing ourselves in this way would threaten our achievements. We call this the argument against enhancement from achievement.
Lisa Forsberg, Anthony Skelton
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Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate
Frontiers in Cell and Developmental Biology, 2020 Enhancers are cis-regulatory elements in the genome that cooperate with promoters to control target gene transcription. Unlike promoters, enhancers are not necessarily adjacent to target genes and can exert their functions regardless of enhancer ...
Preston R. Arnold +3 more
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Frontiers in Immunology, 2022 γδ T cells play important roles in immune responses by rapidly producing large quantities of cytokines. Recently, γδ T cells have been found to be involved in tissue homeostatic regulation, playing roles in thermogenesis, bone regeneration and synaptic ...
Alonso Rodríguez-Caparrós +6 more
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Frontiers in Genetics, 2020 The overall aim of the Ovine FAANG project is to provide a comprehensive annotation of the new highly contiguous sheep reference genome sequence (Oar rambouillet v1.0).
Mazdak Salavati +14 more
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Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells
Antioxidants, 2021 Epigenetic aberrations are linked to sporadic breast cancer. Interestingly, certain dietary polyphenols with anti-cancer effects, such as pterostilbene (PTS), have been shown to regulate gene expression by altering epigenetic patterns.
Sadaf Harandi-Zadeh +11 more
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