Results 41 to 50 of about 370,708 (316)
Enhancer annotation summary statistics.
, 2022 A) Genomic coverage by tissue category. B) Adult brain and astrocyte enhancer annotations had the highest genomic coverage compared to fetal, neurosphere, and ESC-derived enhancer annotations. C) Enhancer number by tissue category.
Alex M. Casella (9427789) +2 more
core +1 more source
Psychopharmaceutical Enhancers: Enhancing Identity? [PDF]
Neuroethics, 2009 The use of psychopharmaceuticals to enhance human mental functioning such as cognition and mood has raised a debate on questions regarding identity and authenticity. While some hold that psychopharmaceutical substances can help users to ‘become who they really are’ and thus strengthen their identity and authenticity, others believe that the substances ...
Bolt, Ineke, Schermer, Maartje
openaire +2 more sources
, 2022 This study aimed to uncover transcription factors that regulate super-enhancers involved in glucose metabolism reprogramming in poorly differentiated thyroid carcinoma (PDTC).
Yongrui Du (13826368) +3 more
core +1 more source
A SNP uncoupling Mina expression from the TGFβ signaling pathway
Immunity, Inflammation and Disease, 2018 Introduction Mina is a JmjC family 2‐oxoglutarate oxygenase with pleiotropic roles in cell proliferation, cancer, T cell differentiation, pulmonary inflammation, and intestinal parasite expulsion.
Shang L. Lian +4 more
doaj +1 more source
DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL
Pharmaciana, 2013 Dimethylsulfoxide (DMSO) has been intensively studied the 19th century. This substance is used as a medicine and solve. It can also be used as an absorption enhancer of various drugs, either synthetical or herbal medicines.
Resty Annisa Damayanti, Tedjo Yuwono
doaj +1 more source
, 2023 BackgroundSuper-enhancer (SE) refers to a regulatory element with super transcriptional activity, which can enrich transcription factors and drive gene expression. SE-related genes play an important role in the pathogenesis of malignant tumors, including
Qian Guo (107009) +15 more
core +1 more source
Splicing of enhancer-associated lincRNAs contributes to enhancer activity [PDF]
, 2020 Transcription is common at active mammalian enhancers sometimes giving rise to stable enhancer-associated long intergenic noncoding RNAs (elincRNAs).
Tan, J.Y. +11 more
core +1 more source
Optimised plasmids for sustained transgene expression in vivo [PDF]
, 2010 Plasmid based gene therapy approaches often lack long term transgene expression in vivo due to silencing or loss of the vector. One way to overcome these limitations is to combine non-silenced promoters with strong viral enhancers.
Magnusson, Terese
core +1 more source
Frontiers in Immunology, 2019 CD8 expression in T lymphocytes is tightly regulated by the activity of at least six Cd8 enhancers (E8I-E8VI), however their complex developmental stage-, subset-, and lineage-specific interplays are incompletely understood.
Alexandra Franziska Gülich +9 more
doaj +1 more source
Targeted screening of genetic associations with COVID-19 susceptibility and severity
Frontiers in Genetics, 2022 The COVID-19 pandemic has resulted in great morbidity and mortality worldwide and human genetic factors have been implicated in the susceptibility and severity of COVID-19.
Ping Li +9 more
doaj +1 more source