Results 51 to 60 of about 9,209,436 (353)
Enhancers, enhancers – from their discovery to today’s universe of transcription enhancers [PDF]
Biological Chemistry, 2015 AbstractTranscriptional enhancers are short (200–1500 base pairs) DNA segments that are able to dramatically boost transcription from the promoter of a target gene. Originally discovered in simian virus 40 (SV40), a small DNA virus, transcription enhancers were soon also found in immunoglobulin genes and other cellular genes as key determinants of cell-
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Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3’ regulatory regions and its conservation in mammals [PDF]
, 2016 Regulatory regions in the genome can act through a variety of mechanisms that range from the occurrence of histone modifications to the presence of protein-binding loci for self-annealing sequences.
Cacchione, Stefano +9 more
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YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Cell, 2017 SUMMARY There is considerable evidence that chromosome structure plays important roles in gene control, but we have limited understanding of the proteins that contribute to structural interactions between gene promoters and their enhancer elements. Large
A. Weintraub +15 more
semanticscholar +1 more source
The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine, 2019 The range of opportunities people enjoy in life largely depends on social, biological, and genetic factors for which individuals are not responsible. Philosophical debates about equality of opportunities have focussed mainly on addressing social determinants of inequalities.
Giubilini A., Minerva F.
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Cell-specific expression of the FAP gene is regulated by enhancer elements
Frontiers in Molecular Biosciences, 2023 Fibroblast activation protein (FAP) is an integral membrane serine protease that acts as both dipeptidyl peptidase and collagenase. In recent years, FAP has attracted considerable attention due to its specific upregulation in multiple types of tumor cell
Dina V. Antonova +11 more
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A high-gain cell enhancer [PDF]
, 1992 A cell enhancer that offers a combination of high-grain and high output power with extremely good linearity is described. The prototype repeater offers an active gain of at least 100 dB over a bandwidth of several megahertz.
McGeehan, JP, Slingsby, WT
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Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Cell, 2014 SUMMARY Macrophages are critical for innate immune defense and also control organ homeostasis in a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and microenvironment on chromatin state and whether chromatin ...
Yonit Lavin +7 more
semanticscholar +1 more source
Transcriptional complex assembly represented in SBGN PD [PDF]
, 2010 This poster shows how transcriptional complex assembly can be represented in SBGN Process Description language.
Alexander Mazein +2 more
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A SNP uncoupling Mina expression from the TGFβ signaling pathway
Immunity, Inflammation and Disease, 2018 Introduction Mina is a JmjC family 2‐oxoglutarate oxygenase with pleiotropic roles in cell proliferation, cancer, T cell differentiation, pulmonary inflammation, and intestinal parasite expulsion.
Shang L. Lian +4 more
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DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL
Pharmaciana, 2013 Dimethylsulfoxide (DMSO) has been intensively studied the 19th century. This substance is used as a medicine and solve. It can also be used as an absorption enhancer of various drugs, either synthetical or herbal medicines.
Resty Annisa Damayanti, Tedjo Yuwono
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