Results 111 to 120 of about 3,558,527 (312)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PROMOTION TOOLS USED BY HOUSEHOLD DEALING WITH FARM TOURISM IN THE KUJAWY AND POMERANIE PROVINCES OF POLAND [PDF]

open access: yesJournal of Central European Agriculture, 2009
The aim of article was to show the importance of information technology in a farm tourism household. The research focused on the use of internet tools for self-development and promotion.
Małgorzata ZAJDEL   +1 more
doaj  

Job Characteristics and Labor Market Discrimination in Promotions: New Theory and Empirical Evidence [PDF]

open access: yes, 2007
[Excerpt] We present new theory and the first empirical test of promotion discrimination models based on job assignment signaling. In our theory, promotions serve as signals of worker ability, and job hierarchies differ in the degree to which tasks vary ...
DeVaro, Jed, Ghosh, Suman, Zoghi, Cindy
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Strategic Export Promotion [PDF]

open access: yes
This paper provides a general characterization of optimal export promoting policies for foreign competitive markets and apply it to strategic trade policy and exchange rate policy.
Federico Etro
core  

Lessons Learnt From WASH Action Research With Practitioners in Four Countries [PDF]

open access: yes, 2016
This is the final report from the Action Research for Learning programme, a three-year initiative (2013 -- 2015), led by IRC, to improve the effectiveness of existing hygiene promotion and community empowerment programmes of selected local Dutch WASH ...
Jeske Verhoeven, Marielle Snell
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Promotion through Connections: Favors or Information?

open access: yes, 2020
Connections appear to be helpful in many contexts such as obtaining a job, a promotion, a grant, a loan or publishing a paper. This may be due to favoritism or to information conveyed by connections.
Bramoullé, Yann, Huremović, Kenan
core  

Influences on Women Counseling Psychology Associate Professors’ Decisions Regarding Pursuit of Full Professorship [PDF]

open access: yes, 2010
Twelve women tenured as associate professors in American Psychological Association–accredited counseling psychology doctoral programs were interviewed regarding their pursuit of promotion to full professor.
Catlin, Lynn A.   +3 more
core   +1 more source

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