Results 31 to 40 of about 1,653,454 (343)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Features of formation and advancement of children's brand [PDF]
In article the role of marketing researches in formation of a children's brand is proved, the children's market of consumer goods is analysed, age segmentation of children's audience is done.
A.A. Kryvonis, A.A. Shubin
doaj
The question is not whether to promote or not to promote, but rather when to promote
Abstract The Klein Karoo National Arts Festival (KKNK) is one of South Africa's largest and most popular arts festivals. The success of the festival is dependent on the number of tickets sold. Therefore, in order to ensure an increase in ticket sales, the festival organisers/marketers need to know how long before the event visitors decide to attend the
Kruger, Martinette, Saayman, Melville
openaire +2 more sources
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
The article aims to present the themes of popular contemporary women’s novels. The contexts for the analyses are stereotypes of sex and commercial expectations.
Bernadetta Darska
doaj
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Cuisine « nissarde » et particularisme niçois
The creation, in 1998, of the registered trade-mark “Cuisine nissarde” by the departmental union of tourism agencies of the « Alpes-Maritimes » (UDOTSI), in order to counterbalance the degradation of the image of the traditional regional cooking and of ...
Aline Brochot
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
MARKETING MIX IN OLTENIA ENERGY COMPLEX [PDF]
Electricity generation in Romania it’s realized in percentage 30 % in OLTENIA ENERGY COMPLEX. This is the biggest producer of energy, end coal in the country. Therefore Marketing mix is very important to ensure that the company grows. The final objective
Păunescu Alberto Nicolae
doaj

