Results 81 to 90 of about 3,362,430 (354)

References: (a) DoD Directive 5110.4, “Washington Headquarters Services (WHS),” [PDF]

reissues Reference (b) to disseminate policies and update responsibilities and procedures for selection of employees covered by merit promotion. 2. APPLICABILITY. See Enclosure 1. 3. POLICY. It is OSD policy that: a.
Subject Merit Promotion
core  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Family doctors and health promotion : do we practise what we preach? [PDF]

, 2006
Introduction: A survey on `Attitudes and Knowledge of General Practitioners (GPs) in Prevention and Health Promotion' was carried out in 2000 by EUROPREV (European Network for Prevention and Health Promotion in General Practice / Family Medicine). Method:
Sammut, Mario R.
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Factors and criteria determining career advancement in the Polish police - internal stakeholders' perspective

Journal of Modern Science
Objectives The purpose of the article and the research conducted is to identify the factors and criteria determining promotion in the Police. Material and methods The research used the diagnostic survey method, survey research technique and an original ...
Bogdan Nogalski, Andrzej Józef Kozłowski, Iwona Zofia Czaplicka-Kozłowska, Agnieszka Szpitter   +3 more
doaj   +1 more source

Acceptability of Condom Promotion and Distribution Among 10-19 Year-Old Adolescents in Mpwapwa and Mbeya Rural Districts, Tanzania. [PDF]

, 2012
\ud The HIV/AIDS pandemic remains a leading challenge for global health. Although condoms are acknowledged for their key role on preventing HIV transmission, low and inappropriate use of condoms persists in Tanzania and elsewhere in Africa.
A Exavery, Acleus SM Ruta, Adiel K Mushi, Amon Exavery, C Joanis, C MacPhail, D Buor, E Maticka-Tyndale, E Vittinghoff, Emmanuel A Makundi, Femina HIP, Filemon Tenu, GiveWell, Godfrey M Mubyazi, Hamisi M Malebo, J Takács, J Whitaker, JE Anderson, JK Papo, John W Ogondiek, Jovitha Rugemalila, Joyce K Ikingura, JP Majra, JS St Lawrence, Julius J Massaga, JZL Ng'weshemi, KS Mnyika, ME Beksinska, MF Gallo, MR Kazaura, Mwelecele N Malecela, N Hearst, National Bureau of Statistics (NBS) [Tanzania], National Bureau of Statistics (NBS), Tanzania: National Census, R Mwakitwange, RJ Hayes, S Agha, S Babalola, S Chapman, SA Sanders, SD Pinkerton, SH Kapiga, Sia Malekia, T Rehle, Tanzania Commission for AIDS (TACAIDS), The Research and Analysis Working Group (R&AWG), The World Bank, UNAIDS, UNAIDS, Victor Wiketye, WHO, WHO, Y Kamugola, YA Amirkhanian   +53 more
core   +2 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Visual Asset Design Promotion Ciwidey Gambung Tea Plantation Agrotourism Area [PDF]

, 2019
Agro Tourism The Gambung Ciwidey tea plantation is one of the agrotourism in Bandung Regency. This agrotourism is located in the Gambung tea plantation. It is unfortunate with the many potentials there but not many people know about the existence of this
Nurusholih, S. (Sonson ), Permana, G. (Gandara )   +1 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source